ArticleBritish journal of cancer2015
The impact of eliminating age inequalities in stage at diagnosis on breast cancer survival for older women.
Article in British journal of cancer, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Concordance with urgent referral guidelines in patients presenting with any of six 'alarm' features of possible cancer: a retrospective cohort study using linked primary care records.BMJ quality & safety · 2022Article
- Estimating restricted mean survival time and expected life-years lost in the presence of competing risks within flexible parametric survival models.BMC medical research methodology · 2021Article
- Diagnosing cancer earlier: reviewing the evidence for improving cancer survival.British journal of cancer · 2015Article
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Authors and funding
5 authors.
Funding
Abstract
backgroundOlder women with breast cancer have poorer relative survival outcomes, but whether achieving earlier stage at diagnosis would translate to substantial reductions in mortality is uncertain.
methodsWe analysed data on East of England women with breast cancer (2006-2010) aged 70+ years. We estimated survival for different stage-deprivation-age group strata using both the observed and a hypothetical stage distribution (assuming that all women aged 75+ years acquired the stage distribution of those aged 70-74 years). We subsequently estimated deaths that could be postponed beyond 5 years from diagnosis if women aged 75+ years had the hypothetical stage distribution. We projected findings to the English population using appropriate age and socioeconomic group weights.
resultsFor a typically sized annual cohort in the East of England, 27 deaths in women with breast cancer aged 75+ years can be postponed within 5 years from diagnosis if their stage distribution matched that of the women aged 70-74 years (4.8% of all 566 deaths within 5 years post diagnosis in this population). Under assumptions, we estimate that the respective number for England would be 280 deaths (5.0% of all deaths within 5 years post diagnosis in this population).
conclusionsThe findings support ongoing development of targeted campaigns aimed at encouraging prompt presentation in older women.
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