ArticleOpen forum infectious diseases2014
Death with tuberculosis in california, 1994-2008.
Article in Open forum infectious diseases, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- Factors associated with severity of pulmonary tuberculosis in people living with and without HIV: a systematic review.BMC infectious diseases · 2026Pooled it
- Tuberculosis disease characteristics associated with mortality, severe morbidity and unsuccessful treatment in people living with HIV treated for tuberculosis - a secondary analysis of the ANRS 12300 Reflate TB2 trial.BMC infectious diseases · 2025Trial
- Contribution of Posttuberculosis Sequelae to Life-Years Lost from Tuberculosis Disease in the United States, 2015-2019.American journal of respiratory and critical care medicine · 2025Article
- Risk factors underlying racial and ethnic disparities in tuberculosis diagnosis and treatment outcomes, 2011-19: a multiple mediation analysis of national surveillance data.The Lancet. Public health · 2024Article
- Risk factors affecting treatment outcomes for pulmonary tuberculosis in Finland 2007-2014: a national cohort study.BMC public health · 2020Article
- Residential urban tree canopy is associated with decreased mortality during tuberculosis treatment in California.The Science of the total environment · 2020Article
- Review of tuberculosis treatment outcome reporting system in Denmark, a retrospective study cohort study from 2009 through 2014.BMC health services research · 2020Review
- Characteristics and predictors for tuberculosis related mortality in Denmark from 2009 through 2014: A retrospective cohort study.PloS one · 2020Article
- Tuberculosis Regional Training and Medical Consultation Centers in the United States: Characteristics, outcomes, and quality of medical consultations, June 1, 2010 - May 31, 2014.Journal of clinical tuberculosis and other mycobacterial diseases · 2019Article
- Tuberculosis Mortality in the United States: Epidemiology and Prevention Opportunities.Annals of the American Thoracic Society · 2018Article
- Traffic-Related Air Pollution and All-Cause Mortality during Tuberculosis Treatment in California.Environmental health perspectives · 2017Article
- Clinical Impact on Tuberculosis Treatment Outcomes of Discordance Between Molecular and Growth-Based Assays for Rifampin Resistance, California 2003-2013.Open forum infectious diseases · 2016Article
- Treatment of Active Tuberculosis in Chicago, 2008-2011: The Role of Public Health Departments.PloS one · 2016Article
- Tuberculosis Elimination Efforts in the United States in the Era of Insurance Expansion and the Affordable Care Act.Public health reports (Washington, D.C. : 1974)Article
- Sociodemographic and Clinical Risk Factors Associated With Tuberculosis Mortality in the United States, 2009-2013.Public health reports (Washington, D.C. : 1974)Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundIdentifying factors associated with tuberculosis (TB) deaths will inform efforts to prevent deaths.
methodsWe examined deaths among patients with culture-confirmed TB reported to the California TB Registry during 1994-2008. We calculated the age-adjusted percentage of deaths before and during TB treatment and estimated trends. We constructed multivariable logistic regression models to identify factors associated with death during treatment.
resultsOf 40 125 patients with culture-confirmed TB, 4565 (11%) died: 1146 (25%) died before treatment started, and 3419 (75%) died during treatment. The age-adjusted percentage of patients who died before and during treatment declined from 1994 to 2008 (3.5% to 2%, and 10.4% to 7.2%, respectively, both P < .0001). We identified several risk factors for death that may be addressed with public health efforts: acquired multidrug resistance (adjusted odds ratio [aOR] = 4.67; 95% confidence interval [CI], 2.09-10.45); care in the private sector (aOR = 3.08; 95% CI, 2.75-3.44); and an initial treatment regimen of <3 drugs (aOR = 2.07; 95% CI, 1.63-2.64). We identified other risk factors for death that could be used as markers for intensified diagnostic and treatment processes in hospital: human immunodeficiency virus coinfection; meningeal, peritoneal, and disseminated TB; substance use; and abnormal chest radiograph without cavities.
conclusionsIn California, 1 in 9 TB patients died with a potentially curable disease. Public health departments might prevent deaths in patients with TB by strengthening partnerships with private providers, intensifying diagnostic and treatment processes for patients at risk of death in hospital, optimizing treatment regimens for patients with comorbidities, and preventing the acquisition of drug resistance.
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