ArticleOpen forum infectious diseases2014
Aspirin Use for Primary and Secondary Prevention in Human Immunodeficiency Virus (HIV)-Infected and HIV-Uninfected Patients.
Article in Open forum infectious diseases, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 36 citations in OpenAlex.
- Predictors of Cerebral Small-Vessel Disease in Middle-Aged, Virologically Controlled People Living With HIV.Open forum infectious diseases · 2026Article
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- First-ever acute ischemic strokes in HIV-infected persons: A case-control study from stroke units.Annals of clinical and translational neurology · 2024Article
- Evolving mechanisms and presentations of cardiovascular disease in people with HIV: implications for management.Clinical microbiology reviews · 2024Review
- HIV, Combination Antiretroviral Therapy, and Vascular Diseases in Men and Women.JACC. Basic to translational science · 2022Review
- Cardiovascular disease and prevention among people living with HIV in South Florida.Medicine · 2021 · on this mapObservational
- Article
- Contemporary issues and new challenges in chronic kidney disease amongst people living with HIV.AIDS research and therapy · 2020Review
- Characteristics, Prevention, and Management of Cardiovascular Disease in People Living With HIV: A Scientific Statement From the American Heart Association.Circulation · 2019Review
- Stroke in HIV.The Canadian journal of cardiology · 2019Review
- Multimorbidity and care for hypertension, diabetes and HIV among older adults in rural South Africa.Bulletin of the World Health Organization · 2019Article
- Impact of the American College of Cardiology/American Heart Association Cholesterol Guidelines on Statin Eligibility Among Human Immunodeficiency Virus-Infected Individuals.Open forum infectious diseases · 2018Article
- Epidemiology of ischemic heart disease in HIV.Current opinion in HIV and AIDS · 2017Review
- Presence, Characteristics, and Prognostic Associations of Carotid Plaque Among People Living With HIV.Circulation. Cardiovascular imaging · 2017Article
- Suboptimal primary and secondary cardiovascular disease prevention in HIV-positive individuals on antiretroviral therapy.European journal of preventive cardiology · 2017Article
- Coronary Artery Disease in HIV-Infected Patients: Downside of Living Longer.Current atherosclerosis reports · 2017Review
- Pre-clinical carotid atherosclerosis and sCD163 among virally suppressed HIV patients in Botswana compared with uninfected controls.PloS one · 2017Article
- Heart failure in patients with human immunodeficiency virus infection: Epidemiology and management disparities.International journal of cardiology · 2016Article
- Polypharmacy in older adults with human immunodeficiency virus infection compared with the general population.Clinical interventions in aging · 2016Article
- Graying of the HIV epidemic: a challenge for inpatient medicine providers.Journal of community hospital internal medicine perspectives · 2015Article
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundHuman immunodeficiency virus (HIV) infection is associated with increased risk of myocardial infarction (MI). The use of aspirin for primary and secondary MI prevention in HIV infection has not been extensively studied.
methodsWe performed a cross-sectional study of 4037 patients infected with HIV and 36 338 demographics-matched control patients in the Partners HealthCare System HIV cohort. We developed an algorithm to ascertain rates of nonepisodic acetylsalicylic acid (ASA) use using medication and electronic health record free text data. We assessed rates of ASA use among HIV-infected and HIV-uninfected (negative) patients with and without coronary heart disease (CHD).
resultsRates of ASA use were lower among HIV-infected compared with HIV-uninfected patients (12.4% vs 15.3%, P < .001), with a relatively greater difference among patients with ≥2 CHD risk factors (22.1% vs 42.4%, P < .001). This finding was present among men and among patients in the 30-39 and 40-49 age groups. Among patients with prevalent CHD using ASA for secondary prevention, rates of ASA use were also lower among HIV-infected patients compared with HIV-uninfected patients (51.6% vs 65.4%, P < .001).
conclusionsRates of ASA use were lower among HIV-infected patients compared with controls, with a greater relative difference among those with elevated CHD risk and those with known CHD. Further studies are needed to investigate the optimal strategies for ASA use among patients infected with HIV.
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