Evidence map›Paper›PMID 25734128›Full record

ArticleOpen forum infectious diseases2014

The Linkage Outcomes of a Large-scale, Rapid Transfer of HIV-infected Patients From Hospital-based to Community-based Clinics in South Africa.

Christie Cloete, Susan Regan, Janet Giddy, Tessa Govender, Alison Erlwanger, Melanie R Gaynes, Kenneth A Freedberg, Jeffrey N Katz, Rochelle P Walensky, Elena Losina and 1 more

Abstract read
In one paragraph

Article in Open forum infectious diseases, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

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  3. Evaluation of the impact of PEPFAR transition on retention in care in South Africa's Western Cape Province.South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Christie CloeteMcCord Hospital , Durban , South Africa.
Susan ReganDivision of General Medicine ; Medical Practice Evaluation Center, Department of Medicine.
Janet GiddyMcCord Hospital , Durban , South Africa.
Tessa GovenderMcCord Hospital , Durban , South Africa.
Alison ErlwangerDivision of General Medicine ; Medical Practice Evaluation Center, Department of Medicine.
Melanie R GaynesDivision of General Medicine ; Medical Practice Evaluation Center, Department of Medicine.
Kenneth A FreedbergDivision of General Medicine ; Medical Practice Evaluation Center, Department of Medicine ; Division of Infectious Disease , Massachusetts General Hospital ; Harvard University Center for AIDS Research (CFAR) ; Departments of Biostatistics and Epidemiology , Boston University School of Public Health ; Departments of Epidemiology and Health Policy and Management , Harvard School of Public Health.
Jeffrey N KatzDepartments of Epidemiology and Health Policy and Management , Harvard School of Public Health ; Division of Rheumatology, Department of Medicine, and Department of Orthopedic Surgery , Brigham and Women's Hospital.
Rochelle P WalenskyDivision of General Medicine ; Medical Practice Evaluation Center, Department of Medicine ; Division of Infectious Disease , Massachusetts General Hospital ; Harvard University Center for AIDS Research (CFAR) ; Division of Infectious Disease , Brigham and Women's Hospital , Boston, Massachusetts.
Elena LosinaMedical Practice Evaluation Center, Department of Medicine ; Harvard University Center for AIDS Research (CFAR) ; Departments of Biostatistics and Epidemiology , Boston University School of Public Health ; Division of Rheumatology, Department of Medicine, and Department of Orthopedic Surgery , Brigham and Women's Hospital.
Ingrid V BassettDivision of General Medicine ; Medical Practice Evaluation Center, Department of Medicine ; Division of Infectious Disease , Massachusetts General Hospital ; Harvard University Center for AIDS Research (CFAR).

Funding

The impact of HIV viral diversity and cellular immunity on HIV pathogenesisP30AI060354 · NIAID · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI Daniel Lingwood · 2004 to 2026
$94.4M
Optimizing HIV Care in Less Developed CountriesR01AI058736 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI Kenneth Alan Freedberg, Emily Parker Hyle · 2004 to 2026
$21.5M
Novel Methods to Inform HIV/TB Clinical Trial DevelopmentR01AI093269 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI REDDY, KRISHNA P · 2011 to 2024
$6.8M
Optimizing strategies for universal HIV testingR01MH073445 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI WALENSKY, ROCHELLE P. · 2006 to 2010
$3.3M
Linkage & Retention: A Randomized Trial to Optimize HIV/TB Care in South AfricaR01MH090326 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI BASSETT, INGRID VALERIE · 2010 to 2014
$2.9M
Patient Oriented Research and Mentoring Program in OrthopedicsK24AR057827 · NIAMS · BRIGHAM AND WOMEN'S HOSPITAL · PI LOSINA, ELENA · 2010 to 2019
$1.7M
NIAID NIH HHS P30 AI060354NIAID NIH HHS R01 AI058736NIAMS NIH HHS K24 AR057827NIMH NIH HHS R01 MH073445NIMH NIH HHS R01 MH090326
6 · The paper itself

Abstract

backgroundPresident's Emergency Plan for AIDS Relief (PEPFAR) funding changes have resulted in human immunodeficiency virus (HIV) clinic closures. We evaluated linkage to care following a large-scale patient transfer from a PEPFAR-funded, hospital-based HIV clinic to government-funded, community-based clinics in Durban.

methodsAll adults were transferred between March and June 2012. Subjects were surveyed 5-10 months post-transfer to assess self-reported linkage to the target clinic. We validated self-reports by auditing records at 8 clinics. Overall success of transfer was estimated using linkage to care data for both reached and unreached subjects, adjusted for validation results.

resultsOf the 3913 transferred patients, 756 (19%) were assigned to validation clinics; 659 (87%) of those patients were reached. Among those reached, 468 (71%) had a validated clinic record visit. Of the 46 who self-reported attending a different validation clinic than originally assigned, 39 (85%) had a validated visit. Of the 97 patients not reached, 59 (61%) had a validated visit at their assigned clinic. Based on the validation rates for reached and unreached patients, the estimated success of transfer for the cohort overall was 82%.

conclusionsMost patients reported successful transfer to a community-based clinic, though a quarter attended a different clinic than assigned. Validation of attendance highlights that nearly 20% of patients may not have linked to care and may have experienced a treatment interruption. Optimizing transfers of HIV care to community sites requires collaboration with receiving clinics to ensure successful linkage to care.

Indexed as

community-based clinicslinkage to carePEPFARSouth Africatransfer of HIV care

Identifiers

PMID25734128
PMCPMC4281821

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.