Evidence map›Paper›PMID 25733941›Full record

ReviewPatient related outcome measures2015

Quality of life in adolescent and young adult cancer patients: a systematic review of the literature.

Gwendolyn P Quinn, Vânia Gonçalves, Ivana Sehovic, Meghan L Bowman, Damon R Reed

Registry-linked trialAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Patient related outcome measures, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03778658 (AYA-UNITE), which is not on this map. Cited by 132 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
132citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03778658 nacompletednot on this mapstarted 2020, after this paper: background citation

AYA-UNITE (Utilizing Novel Information Technology to Promote Exercise and Well-Being)

TypeinterventionalSponsorMilton S. Hershey Medical CenterRan2020 to 2022Enrolled7ConditionsAdolescent, Young Adult, Cancer, Physical ActivityArmsPhysical Activity Intervention
3 · Its place in the literature

Who cites it

132 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Guideline
  2. Guideline
  3. Mapping and comparing the quality of life outcomes in childhood and adolescent and young adult cancer survivors: an umbrella review and future directions.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Pooled it
  4. Pooled it
  5. Survivorship care models for breast cancer, colorectal cancer, and adolescent and young adult (AYA) cancer survivors: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2018
    Pooled it
  6. Trial
  7. Trial
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  15. Review
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  18. Addressing and supporting the unmet needs of sarcoma survivors: a qualitative study.International journal of qualitative studies on health and well-being · 2025
    Article
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  20. Article

72 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gwendolyn P QuinnH Lee Moffitt Cancer Center and Research Institute, Department of Health Outcomes and Behavior, Tampa, FL, USA ; Morsani College of Medicine, University of South Florida, Tampa, FL, USA ; H Lee Moffitt Cancer Center and Research Institute, Adolescent Young Adult Oncology Program, Tampa, FL, USA.
Vânia GonçalvesFaculty of Psychology and Educational Sciences, University of Coimbra, Coimbra, Portugal.
Ivana SehovicH Lee Moffitt Cancer Center and Research Institute, Department of Health Outcomes and Behavior, Tampa, FL, USA ; H Lee Moffitt Cancer Center and Research Institute, Adolescent Young Adult Oncology Program, Tampa, FL, USA.
Meghan L BowmanH Lee Moffitt Cancer Center and Research Institute, Department of Health Outcomes and Behavior, Tampa, FL, USA ; H Lee Moffitt Cancer Center and Research Institute, Adolescent Young Adult Oncology Program, Tampa, FL, USA.
Damon R ReedMorsani College of Medicine, University of South Florida, Tampa, FL, USA ; H Lee Moffitt Cancer Center and Research Institute, Adolescent Young Adult Oncology Program, Tampa, FL, USA ; H Lee Moffitt Cancer Center and Research Institute, Department of Sarcoma, Tampa, FL, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAdolescent and young adult (AYA) cancer survivors experience many unique challenges and quality of life (QoL) effects that persist beyond cancer diagnosis and treatment. Due to continuous improvements in technology and cancer treatments resulting in improved survival rates, the identification of late effects, survivorship issues, and QoL is moving to the forefront of cancer research. The goal of this systematic review was to identify key psychosocial factors impacting QoL in AYA oncology populations.

methodsA systematic review of the literature was conducted using combinations of these phrases or keywords: "adolescent and young adult or AYA" AND "health outcomes OR quality of life OR psychology" AND "neoplasm OR cancer OR oncology". A total of 35 articles were included in this review. Studies were classified into two categories: AYA perceptions and stakeholder perceptions.

resultsAYA cancer survivors were more likely to have "worse" or impaired QoL compared with the general population, regardless of other demographic factors. AYAs described both positive and negatives experiences with their medical care, the educational information received, and the supportive care services. Although health care professionals were likely to underestimate or misjudge the health preferences and support needs of AYAs, these perceptions varied across disciplines and levels of experience.

conclusionThe literature is lacking in sufficient evidence-based interventions to improve QoL in AYA cancer populations. Further, the tools to adequately measure QoL in this population are also unsatisfactory. The literature, however, consistently shows agreement regarding the unique needs of this population, indicating a trend toward health care standardization within age ranges or life stages. We suggest the need for AYA-specific programs in health care institutions that comprise a multidisciplinary team that addresses all the unique medical and QoL needs of AYAs.

Indexed as

adolescent and young adultoncologyquality of life

Identifiers

PMID25733941
PMCPMC4337625

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.