ArticleProceedings of the National Academy of Sciences of the United States of America2015
Sequential de novo centromere formation and inactivation on a chromosomal fragment in maize.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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Who cites it
37 citing papers in PubMed, 49 citations in OpenAlex.
- Comparative centromere genomics reveals evolutionary divergence in Solanaceae genomes.Genome biology · 2026Article
- Adaptation of centromeres to breakage through local genomic and epigenomic remodeling in wheat.Genome research · 2025Article
- Stable minichromosome and functional neocentromere derived from rye 7R chromosome arm.BMC plant biology · 2024Article
- Three near-complete genome assemblies reveal substantial centromere dynamics from diploid to tetraploid in Brachypodium genus.Genome biology · 2024Article
- Pan-centromere reveals widespread centromere repositioning of soybean genomes.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Centromere Plasticity With Evolutionary Conservation and Divergence Uncovered by Wheat 10+ Genomes.Molecular biology and evolution · 2023Article
- Synthetic maize centromeres transmit chromosomes across generations.Nature plants · 2023Article
- Non-B-form DNA tends to form in centromeric regions and has undergone changes in polyploid oat subgenomes.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Centromeres: From chromosome biology to biotechnology applications and synthetic genomes in plants.Plant biotechnology journal · 2022Review
- Molecular Dynamics and Evolution of Centromeres in the Genus Equus.International journal of molecular sciences · 2022Review
- Effect of aneuploidy of a non-essential chromosome on gene expression in maize.The Plant journal : for cell and molecular biology · 2022Article
- De novo centromere formation on chromosome fragments with an inactive centromere in maize (Zea mays).Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2021Article
- Sequence of the supernumerary B chromosome of maize provides insight into its drive mechanism and evolution.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Chromosomal variations of Lycoris species revealed by FISH with rDNAs and centromeric histone H3 variant associated DNAs.PloS one · 2021Article
- The Genomics of Plant Satellite DNA.Progress in molecular and subcellular biology · 2021Review
- Rapid Birth or Death of Centromeres on Fragmented Chromosomes in Maize.The Plant cell · 2020Article
- Genome Evolution in Arabideae Was Marked by Frequent Centromere Repositioning.The Plant cell · 2020Article
- Back-spliced RNA from retrotransposon binds to centromere and regulates centromeric chromatin loops in maize.PLoS biology · 2020Article
- Centromere Satellite Repeats Have Undergone Rapid Changes in Polyploid Wheat Subgenomes.The Plant cell · 2019Article
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Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The ability of centromeres to alternate between active and inactive states indicates significant epigenetic aspects controlling centromere assembly and function. In maize (Zea mays), misdivision of the B chromosome centromere on a translocation with the short arm of chromosome 9 (TB-9Sb) can produce many variants with varying centromere sizes and centromeric DNA sequences. In such derivatives of TB-9Sb, we found a de novo centromere on chromosome derivative 3-3, which has no canonical centromeric repeat sequences. This centromere is derived from a 288-kb region on the short arm of chromosome 9, and is 19 megabases (Mb) removed from the translocation breakpoint of chromosome 9 in TB-9Sb. The functional B centromere in progenitor telo2-2 is deleted from derivative 3-3, but some B-repeat sequences remain. The de novo centromere of derivative 3-3 becomes inactive in three further derivatives with new centromeres being formed elsewhere on each chromosome. Our results suggest that de novo centromere initiation is quite common and can persist on chromosomal fragments without a canonical centromere. However, we hypothesize that when de novo centromeres are initiated in opposition to a larger normal centromere, they are cleared from the chromosome by inactivation, thus maintaining karyotype integrity.
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