ArticleNeuropsychiatric disease and treatment2015
One-year follow-up in patients with brainstem infarction due to large-artery atherothrombosis.
Article in Neuropsychiatric disease and treatment, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed, 5 citations in OpenAlex.
- Urinary kallidinogenase for the treatment of cerebral arterial stenosis.Drug design, development and therapy · 2015Trial
- Heart rate and clinical outcome after endovascular treatment in patients with anterior versus posterior circulation large vessel occlusion.Therapeutic advances in neurological disorders · 2026Article
- Multimodal assessment of recovery from coma in a rat model of diffuse brainstem tegmentum injury.NeuroImage · 2019Article
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7 authors at 1 institution in 1 country.
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Abstract
backgroundPosterior circulation infarction accounts for approximately 25% of the ischemic strokes. A number of different conditions may be associated with the development of brainstem infarction. Prognosis and recurrence rate of brainstem infarction due to large-artery atherothrombosis is still controversial.
methodsA total of 826 patients with ischemic stroke were admitted to our clinic during a 15-month period. Patients with clinical and radiological evidence of brainstem infarction were comprehensively assessed with appropriate vascular imaging modalities and for cardiological causes. Subjects with an established diagnosis of large-artery atherothrombosis were followed up for 1 year in terms of prognosis and recurrence rates.
resultsOf the 101 patients with an established brainstem infarction, the diagnostic work-up indicated the presence of large-artery atherothrombosis as the causative factor in 53. A recurrent stroke was detected in the posterior circulation within the first 3 months in 5.8% and within 1 year in 9.8% of these individuals. The 1-year mortality rate was 11.7%. All patients with recurrent stroke had intracranial vascular narrowing at baseline.
conclusionOur findings demonstrate a particularly high rate of recurrence and mortality at 1 year among patients who have a brainstem infarction due to intracranial arterial stenosis.
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