ArticleInternational journal of nanomedicine2015
Binding of plasma proteins to titanium dioxide nanotubes with different diameters.
Article in International journal of nanomedicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 76 citations in OpenAlex.
- The immune-microbe-metal triad: a vicious cycle driving biomaterial corrosion in the oral inflammatory microenvironment.Bioactive materials · 2027Review
- Insight into antibacterial effect of titanium nanotubular surfaces with focus on Staphylococcus aureus and Pseudomonas aeruginosa.Scientific reports · 2024Article
- Multifunctional and bioinspired titanium surface with multilayer nanofilms for novel dental implant applications.Frontiers in chemistry · 2024Article
- Fine-Tuning the Nanostructured Titanium Oxide Surface for Selective Biological Response.ACS applied bio materials · 2023Article
- Fabrication of Antibacterial TiOACS omega · 2022Article
- Effect of Silicon Carbide Coating on Osteoblast Mineralization of Anodized Titanium Surfaces.Journal of functional biomaterials · 2022Article
- Laminin Adsorption and Adhesion of Neurons and Glial Cells on Carbon Implanted Titania Nanotube Scaffolds for Neural Implant Applications.Nanomaterials (Basel, Switzerland) · 2022Article
- Nanoporous Stainless Steel Materials for Body Implants-Review of Synthesizing Procedures.Nanomaterials (Basel, Switzerland) · 2022Review
- Exosomal Composition, Biogenesis and Profiling Using Point-of-Care Diagnostics-Implications for Cardiovascular Disease.Frontiers in cell and developmental biology · 2022Review
- Bio-Performance of Hydrothermally and Plasma-Treated Titanium: The New Generation of Vascular Stents.International journal of molecular sciences · 2021Article
- Titanium dioxide nanotubes as drug carriers for infection control and osteogenesis of bone implants.Drug delivery and translational research · 2021Review
- Use of Plasma Technologies for Antibacterial Surface Properties of Metals.Molecules (Basel, Switzerland) · 2021Review
- Impedimetric Detection of Femtomolar Levels of Interleukin6, Interleukin 8, and Tumor Necrosis Factor Alpha Based on Thermally Modified Nanotubular Titanium Dioxide Arrays.Nanomaterials (Basel, Switzerland) · 2020Article
- Comparative investigations ofRSC advances · 2020Article
- Crystallized TiONanomaterials (Basel, Switzerland) · 2020Review
- Article
- TiOInternational journal of nanomedicine · 2020Article
- Plasma Proteins at the Interface of Dental Implants Modulate Osteoblasts Focal Adhesions Expression and Cytoskeleton Organization.Nanomaterials (Basel, Switzerland) · 2019Article
- Low density lipoprotein adsorption on a titanium surface and its effect on osteoblast behaviors.RSC advances · 2019Article
- Plasma-Induced Crystallization of TiO₂ Nanotubes.Materials (Basel, Switzerland) · 2019Article
Corrections and comments
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Authors and funding
13 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Titanium and titanium alloys are considered to be one of the most applicable materials in medical devices because of their suitable properties, most importantly high corrosion resistance and the specific combination of strength with biocompatibility. In order to improve the biocompatibility of titanium surfaces, the current report initially focuses on specifying the topography of titanium dioxide (TiO2) nanotubes (NTs) by electrochemical anodization. The zeta potential (ζ-potential) of NTs showed a negative value and confirmed the agreement between the measured and theoretically predicted dependence of ζ-potential on salt concentration, whereby the absolute value of ζ-potential diminished with increasing salt concentrations. We investigated binding of various plasma proteins with different sizes and charges using the bicinchoninic acid assay and immunofluorescence microscopy. Results showed effective and comparatively higher protein binding to NTs with 100 nm diameters (compared to 50 or 15 nm). We also showed a dose-dependent effect of serum amyloid A protein binding to NTs. These results and theoretical calculations of total available surface area for binding of proteins indicate that the largest surface area (also considering the NT lengths) is available for 100 nm NTs, with decreasing surface area for 50 and 15 nm NTs. These current investigations will have an impact on increasing the binding ability of biomedical devices in the body leading to increased durability of biomedical devices.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.