ArticleHuman brain mapping2015
Connectivity and functional profiling of abnormal brain structures in pedophilia.
Article in Human brain mapping, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 42 citations in OpenAlex.
- Cognitive profiles of paedophilic behaviour: a meta-analytic and systematic review of developmental vs acquired forms.Frontiers in psychiatry · 2025Pooled it
- Neural correlates of formal thought disorder: An activation likelihood estimation meta-analysis.Human brain mapping · 2017Pooled it
- Forensic neuroimaging in childhood abduction, rape and murder case and trial outcome.Psychiatry, psychology, and law : an interdisciplinary journal of the Australian and New Zealand Association of Psychiatry, Psychology and Law · 2026Article
- Neuroanatomical and Neurocognitive Differences Between the Executive Functions in Child Sexual Offenders: A Systematic Review.Brain sciences · 2025Review
- Hypothalamic volume in pedophilia with or without child sexual offense.European archives of psychiatry and clinical neuroscience · 2023Article
- Altered Neural and Behavioral Response to Sexually Implicit Stimuli During a Pictorial-Modified Stroop Task in Pedophilic Disorder.Biological psychiatry global open science · 2023Article
- Neural processing associated with cognitive empathy in pedophilia and child sexual offending.Social cognitive and affective neuroscience · 2022Article
- Neurodevelopmental Differences, Pedohebephilia, and Sexual Offending: Findings from Two Online Surveys.Archives of sexual behavior · 2022Article
- Identifying Criteria for the Evaluation of the Implications of Brain Reading for Mental Privacy.Science and engineering ethics · 2019Article
- Expectation of sexual images of adults and children elicits differential dorsal anterior cingulate cortex activation in pedophilic sexual offenders and healthy controls.NeuroImage. Clinical · 2019Article
- Simultaneous Transcranial Alternating Current Stimulation and Functional Magnetic Resonance Imaging.Journal of visualized experiments : JoVE · 2017Article
- Evidence for superior neurobiological and behavioral inhibitory control abilities in non-offending as compared to offending pedophiles.Human brain mapping · 2017Article
- Parental and perinatal risk factors for sexual offending in men: a nationwide case-control study.Psychological medicine · 2017Article
- Brain Imaging of Human Sexual Response: Recent Developments and Future Directions.Current sexual health reports · 2017Review
- The Neurobiology and Psychology of Pedophilia: Recent Advances and Challenges.Frontiers in human neuroscience · 2015Review
- A combined behavioral and EEG investigation of facial emotion recognition in sexual offenders against minors.International journal of clinical and health psychology : IJCHPArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 5 institutions in 3 countries.
Funding
Abstract
Despite its 0.5-1% lifetime prevalence in men and its general societal relevance, neuroimaging investigations in pedophilia are scarce. Preliminary findings indicate abnormal brain structure and function. However, no study has yet linked structural alterations in pedophiles to both connectional and functional properties of the aberrant hotspots. The relationship between morphological alterations and brain function in pedophilia as well as their contribution to its psychopathology thus remain unclear. First, we assessed bimodal connectivity of structurally altered candidate regions using meta-analytic connectivity modeling (MACM) and resting-state correlations employing openly accessible data. We compared the ensuing connectivity maps to the activation likelihood estimation (ALE) maps of a recent quantitative meta-analysis of brain activity during processing of sexual stimuli. Second, we functionally characterized the structurally altered regions employing meta-data of a large-scale neuroimaging database. Candidate regions were functionally connected to key areas for processing of sexual stimuli. Moreover, we found that the functional role of structurally altered brain regions in pedophilia relates to nonsexual emotional as well as neurocognitive and executive functions, previously reported to be impaired in pedophiles. Our results suggest that structural brain alterations affect neural networks for sexual processing by way of disrupted functional connectivity, which may entail abnormal sexual arousal patterns. The findings moreover indicate that structural alterations account for common affective and neurocognitive impairments in pedophilia. The present multimodal integration of brain structure and function analyses links sexual and nonsexual psychopathology in pedophilia.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.