Evidence map›Paper›PMID 25732839›Full record

ArticleBiometrics2015

Multivariate sparse group lasso for the multivariate multiple linear regression with an arbitrary group structure.

Yanming Li, Bin Nan, Ji Zhu

Abstract read
In one paragraph

Article in Biometrics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Article
  2. Article
  3. Multivariate Bayesian variable selection for multi-trait genetic fine mapping.Journal of the Royal Statistical Society. Series C, Applied statistics · 2025
    Article
  4. Multi-task Learning for Gaussian Graphical Regressions with High Dimensional Covariates.Journal of computational and graphical statistics : a joint publication of American Statistical Association, Institute of Mathematical Statistics, Interface Foundation of North America · 2024
    Article
  5. Deep network embedding with dimension selection.Neural networks : the official journal of the International Neural Network Society · 2024
    Article
  6. Article
  7. On the Use of Minimum Penalties in Statistical Learning.Journal of computational and graphical statistics : a joint publication of American Statistical Association, Institute of Mathematical Statistics, Interface Foundation of North America · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Feature selection for kernel methods in systems biology.NAR genomics and bioinformatics · 2022
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yanming LiDepartment of Biostatistics, University of Michigan, Ann Arbor, Michigan, 48109, U.S.A.
Bin NanDepartment of Biostatistics, University of Michigan, Ann Arbor, Michigan, 48109, U.S.A.
Ji ZhuDepartment of Statistics, University of Michigan, Ann Arbor, Michigan, 48109, U.S.A.

Funding

High-Dimensional Data Issues in Aging ResearchR01AG036802 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI NAN, BIN · 2010 to 2013
$1.1M
NIA NIH HHS R01 AG036802NIA NIH HHS R01-AG036802
6 · The paper itself

Abstract

We propose a multivariate sparse group lasso variable selection and estimation method for data with high-dimensional predictors as well as high-dimensional response variables. The method is carried out through a penalized multivariate multiple linear regression model with an arbitrary group structure for the regression coefficient matrix. It suits many biology studies well in detecting associations between multiple traits and multiple predictors, with each trait and each predictor embedded in some biological functional groups such as genes, pathways or brain regions. The method is able to effectively remove unimportant groups as well as unimportant individual coefficients within important groups, particularly for large p small n problems, and is flexible in handling various complex group structures such as overlapping or nested or multilevel hierarchical structures. The method is evaluated through extensive simulations with comparisons to the conventional lasso and group lasso methods, and is applied to an eQTL association study.

Indexed as

Linear ModelsMultivariate AnalysisAlgorithmsBiometryComputer SimulationGenes, FungalGenetic Association StudiesHumansQuantitative Trait LociSaccharomyces cerevisiaeCoordinate descent algorithmEQTLGenetic associationHigh-dimensional dataOracle inequalitiesSparsity

Identifiers

PMID25732839
PMCPMC4479976

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.