ArticleScientific reports2015
All-optical broadband ultrasonography of single cells.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 69 citations in OpenAlex.
- Optoacoustic lenses for lateral sub-optical resolution elasticity imaging.Photoacoustics · 2025Article
- Parallel imaging with phonon microscopy using a multi-core fibre bundle detection.Photoacoustics · 2023Article
- Principles and advances in ultrafast photoacoustics; applications to imaging cell mechanics and to probing cell nanostructure.Photoacoustics · 2023Article
- Efficient pump-probe sampling with a single-cavity dual-comb laser: Application in ultrafast photoacoustics.Photoacoustics · 2023Article
- Non-contact and label-free biomechanical imaging: Stimulated Brillouin microscopy and beyond.Frontiers in physics · 2023Article
- Non-contact elastography methods in mechanobiology: a point of view.European biophysics journal : EBJ · 2022Review
- High spatiotemporal resolution optoacoustic sensing with photothermally induced acoustic vibrations in optical fibres.Nature communications · 2021Article
- Phonon imaging in 3D with a fibre probe.Light, science & applications · 2021Article
- Review
- 3D phonon microscopy with sub-micron axial-resolution.Scientific reports · 2021Article
- Correlative Imaging of Motoneuronal Cell Elasticity by Pump and Probe Spectroscopy.Biophysical journal · 2021Article
- Evaluation of commercial virtually imaged phase array and Fabry-Pérot based Brillouin spectrometers for applications to biology.Biomedical optics express · 2020Article
- Optical and mechanical properties of streptavidin-conjugated gold nanospheres through data mining techniques.Scientific reports · 2020Article
- Apparent attenuation by opto-acoustic defocus in phonon microscopy.Photoacoustics · 2020Article
- Large non-thermal contribution to picosecond strain pulse generation using the photo-induced phase transition in VONature communications · 2020Article
- Deformation Wave Theory and Application to Optical Interferometry.Materials (Basel, Switzerland) · 2020Article
- New insights into the mechanical properties ofBiomedical optics express · 2019Article
- Quantifying cellular forces and biomechanical properties by correlative micropillar traction force and Brillouin microscopy.Biomedical optics express · 2019Article
- Elastography of multicellular spheroids using 3D light microscopy.Biomedical optics express · 2019Article
- Remote imaging of single cell 3D morphology with ultrafast coherent phonons and their resonance harmonics.Scientific reports · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cell mechanics play a key role in several fundamental biological processes, such as migration, proliferation, differentiation and tissue morphogenesis. In addition, many diseased conditions of the cell are correlated with altered cell mechanics, as in the case of cancer progression. For this there is much interest in methods that can map mechanical properties with a sub-cell resolution. Here, we demonstrate an inverted pulsed opto-acoustic microscope (iPOM) that operates in the 10 to 100 GHz range. These frequencies allow mapping quantitatively cell structures as thin as 10 nm and resolving the fibrillar details of cells. Using this non-invasive all-optical system, we produce high-resolution images based on mechanical properties as the contrast mechanisms, and we can observe the stiffness and adhesion of single migrating stem cells. The technique should allow transferring the diagnostic and imaging abilities of ultrasonic imaging to the single-cell scale, thus opening new avenues for cell biology and biomaterial sciences.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.