Evidence map›Paper›PMID 25730731›Full record

ArticleNeuropsychology2015

Habitual prospective memory in HIV disease.

Katie L Doyle, Erica Weber, Erin E Morgan, Shayne Loft, Clint Cushman, Javier Villalobos, Elaine Johnston, Steven Paul Woods, HIV Neurobehavioral Research Program (HNRP) Group

Open access · hybridAbstract read
In one paragraph

Article in Neuropsychology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Prospective memory in youth with perinatally-acquired HIV infection.Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence · 2018
    Article
  9. HIV-associated neurocognitive disorder.Current opinion in infectious diseases · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Katie L DoyleJoint Doctoral Program in Clinical Psychology.
Erica WeberJoint Doctoral Program in Clinical Psychology.
Erin E MorganDepartment of Psychiatry.
Shayne LoftSchool of Psychology.ORCID 0000-0002-5434-0348
Clint CushmanDepartment of Psychiatry.
Javier VillalobosDepartment of Psychiatry.
Elaine JohnstonDepartment of Psychiatry.
Steven Paul WoodsDepartment of Psychiatry.
HIV Neurobehavioral Research Program (HNRP) Group

Funding

STRUCTURAL NEUROIMAGING COREP30MH062512 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Jennifer E Iudicello · 2001 to 2026
$50.4M
Prospective Memory in HIV-1 InfectionR01MH073419 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI WOODS, STEVEN PAUL · 2005 to 2017
$6.6M
Training in Research on Addictions in Interdisciplinary NeuroAIDS (TRAIN)T32DA031098 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Jennifer E Iudicello, DAVID J MOORE · 2011 to 2026
$4.6M
Self-Generation of Prospective Memory in HIV-Infected Methamphetamine UsersF31DA034510 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI WEBER, ERICA · 2012 to 2013
$70k
NIDA NIH HHS F31 DA034510NIDA NIH HHS F31-DA034510NIDA NIH HHS L30 DA032120NIDA NIH HHS L30-DA032120NIDA NIH HHS T32 DA031098NIDA NIH HHS T32-DA31098NIMH NIH HHS P30 MH062512NIMH NIH HHS P30-MH62512NIMH NIH HHS R01 MH073419NIMH NIH HHS R01-MH073419
6 · The paper itself

Abstract

objectiveHIV-associated neurocognitive disorders (HAND) are associated with deficits in prospective memory (PM). However, most PM research in HIV has used single-event tasks as opposed to habitual PM paradigms, which may be more relevant to clinical populations for whom many health-care behaviors must be performed both frequently and routinely.

methodFor the current study, we examined habitual PM and its associations with real-world functioning outcomes in 36 HIV+ individuals with HAND (HAND+), 70 HIV+ individuals without HAND (HAND-), and 115 HIV- individuals. The ongoing task consisted of 24 1-min Stroop trial blocks in which the emotive and cognitive load was manipulated. The habitual PM task required participants to press the spacebar once per block, but only after 20 s had elapsed.

resultsA series of MANOVAs covarying for relevant clinicodemographic factors revealed a main effect of study group on habitual PM, such that the HAND+ cohort made significantly more repetition errors than the HIV- and HAND- groups, particularly during early trial blocks. There was no main effect of ongoing task demands, nor was there an interaction between HAND group and task demands. Within the entire HIV+ sample, poorer habitual PM was associated with deficits in learning and dysfunction in real-world outcomes, including medication nonadherence and failures on a naturalistic health-care task.

conclusionFindings indicate that HAND may be associated with deficient internal source monitoring or temporal discrimination for habitual PM output that may play a critical role in real-world functioning, including HIV disease management.

Indexed as

Memory, EpisodicActivities of Daily LivingAdultAIDS Dementia ComplexFemaleHIV InfectionsHumansMaleMemory DisordersMiddle AgedStroop Test

Identifiers

PMID25730731
PMCPMC4558408
OpenAlexW2058703491

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.