ArticleNature neuroscience2015
Internally organized mechanisms of the head direction sense.
Article in Nature neuroscience, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 133 papers.
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Who cites it
133 citing papers in PubMed.
- Sleep EEG oscillations and synaptic plasticity in memory consolidation across NREM and REM sleep.Dialogues in clinical neuroscience · 2027Review
- Bits per Spike as a Betting Game: An interpretable unit for held-out log-likelihood in neural data analysis.ArXiv · 2026Article
- Tracking the Fidelity of Internal Neural Representations with Error-In-Variables Regression.bioRxiv : the preprint server for biology · 2026Article
- Sleep reveals dynamics integrating and segregating movement and stimulus representations in V1.Nature communications · 2026Article
- Ecological Visual Processing in the Mouse.Annual review of neuroscience · 2026Review
- Sensorimotor dynamics of target acquisition and homing in human echolocation.bioRxiv : the preprint server for biology · 2026Article
- Spatial memory performance is associated with region-specific coordination of hippocampo-cortical sleep oscillations.Scientific reports · 2026Article
- Spatial remapping in the subicular complex and entorhinal cortex follows low-dimensional geometric principles.bioRxiv : the preprint server for biology · 2026Article
- Neuronal spiking in the mammalian forebrain is dominated by a heterogeneous ground state.Neuron · 2026Article
- Months-long stability of the head-direction system.Nature · 2026Article
- Directional dynamics in the entorhinal cortex of male mice driven by behavioral constraints.Nature communications · 2026Article
- Article
- Hippocampal synchrony dynamically gates cortical connectivity across brain states.Scientific reports · 2026Article
- Time, space, memory and brain-body rhythms.Nature reviews. Neuroscience · 2026Review
- Article
- Pathological tau alters head direction signaling and induces spatial disorientation.Cell reports · 2025Article
- Octopamine instructs head direction plasticity.bioRxiv : the preprint server for biology · 2025Article
- Projections from the supragenual nucleus to the lateral mammillary and dorsal tegmental nuclei.Brain structure & function · 2025Article
- Visual motion and landmark position align with heading direction in the zebrafish interpeduncular nucleus.Nature communications · 2025Article
- Encoding of interdependent features of head direction and angular head velocity in navigation.PNAS nexus · 2025Article
73 more citing papers are in PubMed but not listed here.
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Authors and funding
4 authors.
Funding
Abstract
The head-direction (HD) system functions as a compass, with member neurons robustly increasing their firing rates when the animal's head points in a specific direction. HD neurons may be driven by peripheral sensors or, as computational models postulate, internally generated (attractor) mechanisms. We addressed the contributions of stimulus-driven and internally generated activity by recording ensembles of HD neurons in the antero-dorsal thalamic nucleus and the post-subiculum of mice by comparing their activity in various brain states. The temporal correlation structure of HD neurons was preserved during sleep, characterized by a 60°-wide correlated neuronal firing (activity packet), both within and across these two brain structures. During rapid eye movement sleep, the spontaneous drift of the activity packet was similar to that observed during waking and accelerated tenfold during slow-wave sleep. These findings demonstrate that peripheral inputs impinge on an internally organized network, which provides amplification and enhanced precision of the HD signal.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.