Trial reportJournal of musculoskeletal & neuronal interactions2015
Acute effects of superimposed electromyostimulation during cycling on myokines and markers of muscle damage.
Trial report in Journal of musculoskeletal & neuronal interactions, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 33 citations in OpenAlex.
- Safety of a Combined WB-EMS and High-Protein Diet Intervention in Sarcopenic Obese Elderly Men.Clinical interventions in aging · 2020Trial
- Effect of whole-body electromyostimulation and / or protein supplementation on obesity and cardiometabolic risk in older men with sarcopenic obesity: the randomized controlled FranSO trial.BMC geriatrics · 2018Trial
- Chronic effects of superimposed electromyostimulation during cycling on aerobic and anaerobic capacity.European journal of applied physiology · 2017Trial
- Impact of Neuromuscular Electrical Stimulation on Biological Markers in Critically Ill Patients: A Systematic Review and Meta-Analysis.Critical care research and practice · 2026Review
- Outcomes Addressed by Whole-Body Electromyostimulation Trials in Sportspeople and Athletes-An Evidence Map Summarizing and Categorizing Current Findings.Sports (Basel, Switzerland) · 2025Review
- Electrical stimulation: a potential alternative to positively impact cerebral health?Frontiers in physiology · 2024Review
- Highlighting the idea of exerkines in the management of cancer patients with cachexia: novel insights and a critical review.BMC cancer · 2023Review
- A Phase 1 study for safety and pharmacokinetics of BIO101 (20-hydroxyecdysone) in healthy young and older adults.Journal of cachexia, sarcopenia and muscle · 2023Article
- The Potential of Exerkines in Women's COVID-19: A New Idea for a Better and More Accurate Understanding of the Mechanisms behind Physical Exercise.International journal of environmental research and public health · 2022Review
- Acute Effect of Electromyostimulation Superimposed on Running on Maximal Velocity, Metabolism, and Perceived Exertion.Biology · 2022Article
- Training Load Measures and Biomarker Responses during a 7-Day Training Camp in Young Cyclists-A Pilot Study.Medicina (Kaunas, Lithuania) · 2021Article
- A Single Session of Whole-Body Electromyostimulation Increases Muscle Strength, Endurance and proNGF in Early Parkinson Patients.International journal of environmental research and public health · 2021Article
- Whole-Body EMS Superimposed Walking and Nordic Walking on a Treadmill-Determination of Exercise Intensity to Conventional Exercise.Frontiers in physiology · 2021Article
- Modulation of spinal excitability following neuromuscular electrical stimulation superimposed to voluntary contraction.European journal of applied physiology · 2020Article
- (Whole-Body) Electromyostimulation, Muscle Damage, and Immune System: A Mini Review.Frontiers in physiology · 2019Review
- Neuromuscular Electrical Stimulation: A New Therapeutic Option for Chronic Diseases Based on Contraction-Induced Myokine Secretion.Frontiers in physiology · 2019Review
- Training Based on Electrical Stimulation Superimposed Onto Voluntary Contraction Would be Relevant Only as Part of Submaximal Contractions in Healthy Subjects.Frontiers in physiology · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe purpose of the present study was to evaluate the effects of superimposed electromyostimulation (E) during cycling on myokines and markers of muscle damage, as E might be a useful tool to induce a high local stimulus to skeletal muscle during endurance training without performing high external workloads.
methods13 subjects participated in three experimental trials each lasting 60 min in a randomized order. 1) Cycling (C), 2) Cycling with superimposed E (C+E) and 3) E. Interleukin-6 (IL-6), brain-derived neurotrophic factor (BDNF), creatine kinase (CK) and myoglobin were determined before (pre) and 0', 30', 60', 240' and 24h after each intervention.
resultsOnly C+E caused significant increases in levels of CK and myoglobin. BDNF and IL-6 significantly increased after C and C+E, however increases for IL-6 were significantly higher after C+E compared to C.
conclusionThe present study showed that superimposed E during cycling might be a useful tool to induce a high local stimulus to skeletal muscle even when performing low to moderate external workloads. This effect might be due the activation of additional muscle fibers and mild eccentric work due to the concomitant activation of agonist and antagonist. However the higher load to skeletal muscle has to be taken into account.
Indexed as
Identifiers
25730652PMC5123608W46449915What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.