Evidence map›Paper›PMID 25730587›Full record

Trial reportCancer nursing

Evaluation of the Impact of Human Papillomavirus DNA Self-sampling on the Uptake of Cervical Cancer Screening.

Eliza L Y Wong, Paul K S Chan, Josette S Y Chor, Annie W L Cheung, Fenwei Huang, Samuel Y S Wong

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Cancer nursing. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 5 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 5 syntheses or guidelines pooled it, 37 citations in OpenAlex.

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  11. Cervical dysplasia among migrant women with female genital mutilation/cutting type III: A cross-sectional study.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Eliza L Y WongAuthor Affiliations: The Jockey Club School of Public Health and Primary Care (Drs E.L.Y. Wong, Chor, and Y. S. Wong and Mss Cheung and Huang) and Department of Microbiology (Dr Chan), The Chinese University of Hong Kong, Shatin, New Territories.
Paul K S Chan
Josette S Y Chor
Annie W L Cheung
Fenwei Huang
Samuel Y S Wong
Chinese University of Hong Kong · HK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe rate of uptake of the Papanicolaou (Pap) smear is generally low. Its causal relationship with human papillomavirus (HPV) DNA allows HPV DNA self-sampling to be used as an alternative screening tool for cervical cancer.

objectivesThis study explored the acceptability of HPV DNA self-sampling and its impact on the rate of compliance with cervical cancer screening.

methodsA crossover randomized clinical trial was conducted in community-based clinics. Participants were allocated to 1 of the following 2 arms: arm 1: self-sampling before a Pap smear; and arm 2: a Pap smear before self-sampling. After completing the 2 screening methods, participants in each arm took part in face-to-face interviews using standardized, structured questionnaire.

resultsThe participants accepted both self-sampling (7.7/10) and a Pap smear (7.8/10) for cervical cancer screening. However, participants without previous experience of Pap smears or who had more than 2 sexual partners preferred self-sampling (P < .05). The participants expressed overall positive feelings toward self-sampling, and there was good agreement in HPV detection between the 2 screening methods (κ = 0.65). We estimate that the introduction of HPV DNA self-sampling could increase the future rate of uptake of cervical cancer screening by 6.5% and would entail lower costs.

conclusionHuman papillomavirus DNA self-sampling could be an alternative screening method to increase the coverage of cervical cancer screening. IMPLICATIONS FOR PRACTICE: Human papillomavirus DNA self-sampling could overcome the barriers raised by Pap smears and enhance the coverage of cervical cancer screening. Promotional publicity and education are essential.

Indexed as

Human Papillomavirus DNA TestsAdultAgedCross-Over StudiesDNA, ViralEarly Detection of CancerFemaleHumansMiddle AgedPapanicolaou TestPapillomaviridaePapillomavirus InfectionsSelf CareUterine Cervical NeoplasmsDNA, Viral

Identifiers

PMID25730587
PMCPMC4892762
OpenAlexW2325859019

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.