Evidence map›Paper›PMID 25730182›Full record

ReviewBone marrow transplantation2015

Related hematopoietic cell donor care: is there a role for unrelated donor registries?

C Anthias, S M van Walraven, B S Sørensen, G N de Faveri, M Fechter, J Cornish, A Bacigalupo, C Müller, M Boo, B E Shaw

Abstract readReview
PubMed Publisher
In one paragraph

Review in Bone marrow transplantation, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Observational
  3. Article
  4. Review
  5. Discussing and managing hematologic germ line variants.Hematology. American Society of Hematology. Education Program · 2016
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 9 institutions in 7 countries.

C AnthiasAnthony Nolan Research Institute, UCL Cancer Centre, London, UK.
S M van WalravenEuropdonor Foundation, Leiden, The Netherlands.
B S SørensenDepartment of Clinical Immunology, Aarhus University Hospital, Skejby, Denmark.
G N de FaveriSwiss Blood stem cells, Bern, Switzerland.
M FechterEuropdonor Foundation, Leiden, The Netherlands.
J CornishDepartment of Haematology, Bristol Royal Hospital for Children, Bristol, UK.
A BacigalupoDivision of Hematology and Bone Marrow Transplantation, IRCCS San Martino, Genova, Italy.
C Müller1] Zentrales Knochenmarkspender-Register für Deutschland, Ulm, Germany [2] Deutsches Register für Stammzelltransplantationen (DRST), Ulm, Germany.
M BooNational Marrow Donor Program, Minneapolis, MN, USA.
B E Shaw1] Anthony Nolan Research Institute, UCL Cancer Centre, London, UK [2] Department of Haemato-oncology, The Royal Marsden Hospital Downs Rd, Sutton, UK.
Europdonor Foundation · NLAarhus University Hospital · DKAnthony Nolan · GBBristol Royal Hospital for Children · GBGerman National Bone Marrow Donor Registry · DENational Marrow Donor Program · USOspedale Policlinico San Martino · ITRoyal Marsden Hospital · GBSwiss Red Cross · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In almost half of allogeneic hematopoietic progenitor cell (HPC) transplants, a related donor (RD) is used, yet a lack of standardized guidelines means that their care is heterogeneous. Changes to regulatory standards aim to improve uniformity, but adherence to these regulations can prove logistically difficult for the transplant centers (TCs) managing RDs. Discussion has ensued around possible alternative models of related donor care and a session at the European Society for Blood and Marrow Transplantation (EBMT) annual meeting in 2013 debated the question of whether a role exists for unrelated donor registries in the management of 'related' donors. In this overview, we discuss the issues raised at this debate and the pros and cons of donor registry involvement in various aspects of RD management. By examining existing models of related donor care that have been adopted by members of the World Marrow Donor Association (WMDA), we look for ways to enhance and homogenize RD care, while also enabling transplant centers to meet standards required for mandatory accreditation.

Indexed as

Hematopoietic Stem CellsHematopoietic Stem Cell TransplantationRegistriesUnrelated DonorsCongresses as TopicHumans

Identifiers

PMID25730182
OpenAlexW2045097974

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.