Evidence map›Paper›PMID 25729778›Full record

ArticleStatistical atlases and computational models of the heart. STACOM (Workshop)2015

Left Ventricular Diastolic and Systolic Material Property Estimation from Image Data: LV Mechanics Challenge.

Adarsh Krishnamurthy, Christopher Villongco, Amanda Beck, Jeffrey Omens, Andrew McCulloch

Abstract read
In one paragraph

Article in Statistical atlases and computational models of the heart. STACOM (Workshop), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Statistical Atlas-Based Surrogate Model of Biventricular Wall Mechanics.bioRxiv : the preprint server for biology · 2026
    Article
  2. Article
  3. An Atlas-Based Analysis of Biventricular Mechanics in Tetralogy of Fallot.Statistical atlases and computational models of the heart. STACOM (Workshop) · 2022
    Article
  4. Optimization Framework for Patient-Specific Cardiac Modeling.Cardiovascular engineering and technology · 2019
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Adarsh Krishnamurthy
Christopher Villongco
Amanda Beck
Jeffrey Omens
Andrew McCulloch

Funding

National Biomedical Computation Resource - Competitive Revision SupplementP41GM103426 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI AMARO, ROMMIE E · 2012 to 2019
$14.0M
The Cardiac Atlas ProjectR01HL121754 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MCCULLOCH, ANDREW D., OMENS, JEFFREY H. · 2014 to 2023
$5.0M
Multi-Scale Modeling of the Failing Heart for Cardiac Rysynchronization TherapyR01HL096544 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MCCULLOCH, ANDREW D. · 2009 to 2013
$1.8M
NHLBI NIH HHS R01 HL096544NHLBI NIH HHS R01 HL121754NIGMS NIH HHS P41 GM103426
6 · The paper itself

Abstract

Cardiovascular simulations using patient-specific geometries can help researchers understand the mechanical behavior of the heart under different loading or disease conditions. However, to replicate the regional mechanics of the heart accurately, both the nonlinear passive and active material properties must be estimated reliably. In this paper, automated methods were used to determine passive material properties while simultaneously computing the unloaded reference geometry of the ventricles for stress analysis. Two different approaches were used to model systole. In the first, a physiologically-based active contraction model [1] coupled to a hemodynamic three-element Windkessel model of the circulation was used to simulate ventricular ejection. In the second, developed active tension was directly adjusted to match ventricular volumes at end-systole while prescribing the known end-systolic pressure. These methods were tested in four normal dogs using the data provided for the LV mechanics challenge [2]. The resulting end-diastolic and end-systolic geometry from the simulation were compared with measured image data.

Indexed as

Finite Element Methodmesh generationparameter estimationunloaded geometry

Identifiers

PMID25729778
PMCPMC4339056

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.