ArticleKorean journal of pediatrics2015
Molecular typing of uropathogenic Escherichia coli isolated from Korean children with urinary tract infection.
Article in Korean journal of pediatrics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Global Extraintestinal Pathogenic Escherichia coli (ExPEC) Lineages.Clinical microbiology reviews · 2019Pooled it
- Genotypic Diversity and Antimicrobial Resistance Profiles of Multidrug-ResistantInternational journal of molecular sciences · 2026Article
- Molecular characterization of uropathogenicJournal of veterinary science · 2025Article
- The genotypic and phenotypic characteristics contributing to high virulence and antibiotics resistance in Escherichia coli O25-B2-ST131 in comparison to non- O25-B2-ST131.BMC pediatrics · 2023Article
- ESBL-Producing and Non-ESBL-ProducingInfection and drug resistance · 2023Article
- Review
- Comparative Characteristics and Pathogenic Potential ofLife (Basel, Switzerland) · 2022Article
- D-Mannoside FimH Inhibitors as Non-Antibiotic Alternatives for UropathogenicAntibiotics (Basel, Switzerland) · 2021Article
- Comparative Characteristics and Zoonotic Potential of Avian PathogenicMicroorganisms · 2021Article
- Dissemination of different sequence types lineages harboringIranian journal of basic medical sciences · 2020Article
- Frequency of Antimicrobial Resistance and Class 1 and 2 Integrons inIranian journal of pharmaceutical research : IJPR · 2020Article
- Whole-genome analysis of extraintestinalMicrobial genomics · 2020Article
- Genotypic analysis of uropathogenic Escherichia coli to understand factors that impact the prevalence of β-lactam-resistant urinary tract infections in a community.Journal of global antimicrobial resistance · 2019Article
- Phenotypic and Genotypic Characterization ofJournal of clinical medicine · 2019Article
- Diversity and Population Overlap between Avian and Human Escherichia coli Belonging to Sequence Type 95.mSphere · 2019Article
- UropathogenicKorean journal of pediatrics · 2017Article
- Article
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4 authors.
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Abstract
purposeWe investigated the molecular types of uropathogenic Escherichia coli (UPEC) by using conventional phylogrouping, multilocus sequence typing (MLST), and fimH genotyping.
methodsSamples of patients younger than 18 years of age were collected from the Chung-Ang University Hospital over 2 years. Conventional phylogenetic grouping for UPEC strains was performed by polymerase chain reaction (PCR). Bacterial strain sequence types (STs) were classified on the basis of the results of partial sequencing of seven housekeeping genes. In addition, we analyzed nucleotide variations in a 424-base pair fragment of fimH, a major virulence factor in UPEC.
resultsSixty-four UPEC isolates were analyzed in this study. Phylogenetic grouping revealed that group B2 was the most common type (n=54, 84%). We identified 16 distinctive STs using MLST. The most common STs were ST95 (35.9%), ST73 (15.6%), ST131 (12.5%), ST69 (7.8%), and ST14 (6.3%). Fourteen fimH allele types were identified, of which 11 had been previously reported, and the remaining three were identified in this study. f1 (n=28, 45.2%) was found to be the most common allele type, followed by f6 and f9 (n=7, 11.3% each). Comparative analysis of the results from the three different molecular typing techniques revealed that both MLST and fimH typing generated more discriminatory UPEC types than did PCR-based phylogrouping.
conclusionWe characterized UPEC molecular types isolated from Korean children by MLST and fimH genotyping. fimH genotyping might serve as a useful molecular test for large epidemiologic studies of UPEC isolates.
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