Evidence map›Paper›PMID 25729059›Full record

ReviewPhysiology (Bethesda, Md.)2015

The cerebral circulation during pregnancy: adapting to preserve normalcy.

Abbie C Johnson, Marilyn J Cipolla

Open access · greenAbstract readReview
In one paragraph

Review in Physiology (Bethesda, Md.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 67 citations in OpenAlex.

  1. Guidelines for assessing maternal cardiovascular physiology during pregnancy and postpartum.American journal of physiology. Heart and circulatory physiology · 2024
    Guideline
  2. Article
  3. Traumatic brain injury in obstetric patients: challenges and management strategiesRevista colombiana de obstetricia y ginecologia · 2025
    Review
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  15. Sexual differences in mitochondrial and related proteins in rat cerebral microvessels: A proteomic approach.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Abbie C JohnsonDepartment of Neurological Sciences, University of Vermont College of Medicine, Burlington, Vermont.
Marilyn J CipollaDepartment of Neurological Sciences, University of Vermont College of Medicine, Burlington, Vermont Marilyn.Cipolla@uvm.edu.
University of Vermont · US

Funding

The Role of the Blood Brain Barrier in Seizure During Pregnancy and PreeclampsiaR01NS045940 · NINDS · UNIVERSITY OF VERMONT &ST AGRIC COLLEGE · PI CIPOLLA, MARILYN J · 2003 to 2018
$4.6M
NINDS NIH HHS R01 NS045940
6 · The paper itself

Abstract

The adaptation of the brain and cerebral circulation to pregnancy are unique compared with other organs and circulatory systems, ultimately functioning to maintain brain homeostasis. In this review, the effect of pregnancy on critical functions of the cerebral circulation is discussed, including changes occurring at the endothelium and blood-brain barrier, and changes in the structure and function of cerebral arteries and arterioles, hemodynamics, and cerebral blood flow autoregulation.

Indexed as

Cerebrovascular CirculationHemodynamicsAnimalsArteriolesBlood-Brain BarrierBrainCerebral ArteriesEndothelium, VascularFemaleHomeostasisHumansPregnancySignal Transduction

Identifiers

PMID25729059
PMCPMC5504451
OpenAlexW2049713589

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.