Evidence map›Paper›PMID 25728472›Full record

Trial reportNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology2015

GABA Deficits Enhance the Psychotomimetic Effects of Δ9-THC.

Rajiv Radhakrishnan, Patrick D Skosnik, Jose Cortes-Briones, R Andrew Sewell, Michelle Carbuto, Ashley Schnakenberg, John Cahill, Fred Bois, Handan Gunduz-Bruce, Brian Pittman and 2 more

Open access · bronzeAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 3 pooled it
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 3 syntheses or guidelines pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. Review
  7. Article
  8. Article
  9. The Construct of Medical and Non-Medical Marijuana-Critical Review.International journal of environmental research and public health · 2022
    Review
  10. Article
  11. Review
  12. Review
  13. Adolescent ΔBiological psychiatry · 2019
    Article
  14. Review
  15. New vistas on cannabis use disorder.Neuropharmacology · 2017
    Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Rajiv Radhakrishnan1] Psychiatry Service, VA Connecticut Healthcare System, West Haven, CT, USA [2] Abraham Ribicoff Research Facilities, Connecticut Mental Health Center, New Haven, CT, USA [3] Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.
Patrick D Skosnik1] Psychiatry Service, VA Connecticut Healthcare System, West Haven, CT, USA [2] Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.
Jose Cortes-Briones1] Psychiatry Service, VA Connecticut Healthcare System, West Haven, CT, USA [2] Abraham Ribicoff Research Facilities, Connecticut Mental Health Center, New Haven, CT, USA [3] Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.
R Andrew Sewell1] Psychiatry Service, VA Connecticut Healthcare System, West Haven, CT, USA [2] Abraham Ribicoff Research Facilities, Connecticut Mental Health Center, New Haven, CT, USA [3] Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.
Michelle Carbuto1] Psychiatry Service, VA Connecticut Healthcare System, West Haven, CT, USA [2] Abraham Ribicoff Research Facilities, Connecticut Mental Health Center, New Haven, CT, USA [3] Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.
Ashley Schnakenberg1] Psychiatry Service, VA Connecticut Healthcare System, West Haven, CT, USA [2] Abraham Ribicoff Research Facilities, Connecticut Mental Health Center, New Haven, CT, USA [3] Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.
John Cahill1] Psychiatry Service, VA Connecticut Healthcare System, West Haven, CT, USA [2] Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.
Fred Bois1] Psychiatry Service, VA Connecticut Healthcare System, West Haven, CT, USA [2] Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.
Handan Gunduz-Bruce1] Psychiatry Service, VA Connecticut Healthcare System, West Haven, CT, USA [2] Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.
Brian Pittman1] Abraham Ribicoff Research Facilities, Connecticut Mental Health Center, New Haven, CT, USA [2] Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.
Mohini Ranganathan1] Psychiatry Service, VA Connecticut Healthcare System, West Haven, CT, USA [2] Abraham Ribicoff Research Facilities, Connecticut Mental Health Center, New Haven, CT, USA [3] Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.
Deepak Cyril D'Souza1] Psychiatry Service, VA Connecticut Healthcare System, West Haven, CT, USA [2] Abraham Ribicoff Research Facilities, Connecticut Mental Health Center, New Haven, CT, USA [3] Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.
VA Connecticut Healthcare System · USConnecticut Mental Health Center · US

Funding

GABA Deficits and Vulnerability to Cannabinoid-Induced PsychosisR21MH086769 · NIMH · YALE UNIVERSITY · PI D'SOUZA, DEEPAK CYRIL · 2009 to 2010
$374k
NIMH NIH HHS R21 MH086769
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdolescentAdultBrain MappingDissociative DisordersDouble-Blind MethodDronabinolElectroencephalographyEvent-Related Potentials, P300Flumazenilgamma-Aminobutyric AcidHumansMalePain MeasurementPsychiatric Status Rating ScalesPsychotic DisordersPsychotropic DrugsDronabinolFlumazenilgamma-Aminobutyric AcidiomazenilPsychotropic Drugs

Identifiers

PMID25728472
PMCPMC4839528
OpenAlexW2084318079

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.