Evidence map›Paper›PMID 25728373›Full record

SynthesisPalliative & supportive care2015

A systematic review of ovarian cancer and fear of recurrence.

Melissa Ozga, Carol Aghajanian, Shannon Myers-Virtue, Glynnis McDonnell, Sabrina Jhanwar, Shira Hichenberg, Isabel Sulimanoff

Registry-linked trialAbstract readSystematic Review
In one paragraph

Synthesis in Palliative & supportive care, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06070285 (Delving Into the Patterns of Patient Engagement and Trends in Participation Within Recurrent Ovarian Cancer Clinical Trials), which is not on this map. Cited by 60 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06070285 not yet recruitingnot on this mapstarted 2024, after this paper: background citation

Delving Into the Patterns of Patient Engagement and Trends in Participation Within Recurrent Ovarian Cancer Clinical Trials

TypeobservationalSponsorPower Life Sciences Inc.Ran2024 to 2026Enrolled500ConditionsRecurrent Ovarian Cancer
3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. The Role of Emotion-Related Abilities in the Quality of Life of Breast Cancer Survivors: A Systematic Review.International journal of environmental research and public health · 2022
    Pooled it
  2. Pooled it
  3. Trial
  4. Optimising ovarian cancer care: An embedded mixed methods evaluation of a national nurse-led telehealth program.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Predicting psychological distress in advanced ovarian cancer patients during the COVID-19 pandemic.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Exploring the experiences and priorities of women with a diagnosis of ovarian cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Melissa OzgaMemorial Sloan Kettering Cancer Center,New York,New York.
Carol AghajanianMemorial Sloan Kettering Cancer Center,New York,New York.
Shannon Myers-VirtueTemple University and Rutgers Cancer Institute of New Jersey,New Brunswick,New Jersey.
Glynnis McDonnellMemorial Sloan Kettering Cancer Center,New York,New York.
Sabrina JhanwarMemorial Sloan Kettering Cancer Center,New York,New York.
Shira HichenbergMemorial Sloan Kettering Cancer Center,New York,New York.
Isabel SulimanoffMemorial Sloan Kettering Cancer Center,New York,New York.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

objectiveTo assess demographic, medical, and psychological factors that are associated with fear of recurrence (FCR) in ovarian cancer patients.

methodWe searched PubMed, EMBASE, Cochrane, CINAHL, and PsycINFO. For PubMed, a search using Medical Subject Headings (MeSH) was run, as well as a text-word search from 1990 to July of 2014. The search terms used consisted of ovarian terms, fear terms, and recurrence/progression themes. Title and abstract reviews were conducted by two independent reviewers to determine eligibility, and discrepancies were decided by a third reviewer. Full-text reviews of potentially eligible articles were conducted by the review team, which met regularly to ensure the reliability of eligibility ratings across all articles.

resultsA total of 15 articles met our inclusion criteria. Nine were quantitative studies that utilized a cross-sectional design, and the other six included three qualitative studies, two small intervention studies, and one study that utilized content analysis to explore written correspondence among ovarian cancer patients. FCR was reported as a significant concern for both older and younger women at both early and advanced stages. Women were distressed about recurrence at various times during their treatment and posttreatment. FCR was noted to be prevalent around cancer follow-up examinations. Many women reported not receiving adequate support for recurrence. FCR was also shown to be linked in some way to hopelessness, faith/spirituality, and posttraumatic stress disorder (PTSD). FCR was also linked to patients' anxiety about death and dying and uncertainty about the future of their medical health. SIGNIFICANCE OF

resultsThis review demonstrates that FCR is prevalent in the ovarian cancer population. Moreover, cancer recurrence fears are not adequately assessed or treated. More information is needed on the factors that may be related to women's fears about recurrence of ovarian cancer. In addition, a validated measure of FCR among ovarian cancer patients as well as a treatment intervention are needed.

Indexed as

RecurrenceAnxietyCross-Sectional StudiesDisease ProgressionFearFemaleHumansOvarian NeoplasmsSurvivorsFCRFear of recurrenceOvarian cancerRecurrence/progression

Identifiers

PMID25728373
PMCPMC4995592

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.