ArticleJournal of clinical virology : the official publication of the Pan American Society for Clinical Virology2015
Detection of respiratory viruses in gargle specimens of healthy children.
Article in Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Performance of saline and water gargling for SARS-CoV-2 reverse transcriptase PCR testing: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2022Pooled it
- Clinical manifestations in children with parechovirus A and respiratory tract infection.Frontiers in pediatrics · 2026Article
- Diagnostic potential of rhinovirus C using reverse-transcription loop-mediated isothermal amplification (RT-LAMP).International microbiology : the official journal of the Spanish Society for Microbiology · 2025Article
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- Clinical manifestations and outcome of viral acute lower respiratory infection in hospitalised children in Myanmar.BMC infectious diseases · 2022Article
- The temporal pattern and lifestyle associations of respiratory virus infection in a cohort study spanning the first two years of life.BMC pediatrics · 2022Article
- A longitudinal study on respiratory viral infection for healthy volunteers.Health science reports · 2021Article
- Feasibility of a surveillance programme based on gargle samples and pool testing to prevent SARS-CoV-2 outbreaks in schools.Scientific reports · 2021Article
- Pool Testing as a Strategy for Prevention of SARS-CoV-2 Outbreaks in Schools: Protocol for a Feasibility Study.JMIR research protocols · 2021Article
- Seasonal Coronaviruses and Other Neglected Respiratory Viruses: A Global Perspective and a Local Snapshot.Frontiers in public health · 2021Review
- Viral and bacterial coinfection among hospitalized children with respiratory tract infections.American journal of infection control · 2020Article
- Parechovirus A Infections in Healthy Australian Children During the First 2 Years of Life: A Community-based Longitudinal Birth Cohort Study.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020Article
- Neurogenic pulmonary edema following febrile status epilepticus in a 22-month-old infant with multiple respiratory virus co-detection: a case report.BMC infectious diseases · 2020Article
- A 5-year study of human parechoviruses in children living in bad sanitation conditions and non-polio acute flaccid paralysis children from Greece.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2019Article
- Breastfeeding and Respiratory Infections in the First 6 Months of Life: A Case Control Study.Frontiers in pediatrics · 2019Article
- Enterovirus serotypes in patients with central nervous system and respiratory infections in Viet Nam 1997-2010.Virology journal · 2018Article
- Epidemiology and Seasonality of Respiratory Viruses Detected from Children with Respiratory Tract Infections in Wuxi, East China.Medical science monitor : international medical journal of experimental and clinical research · 2018Article
- Update on Human Rhinovirus and Coronavirus Infections.Seminars in respiratory and critical care medicine · 2016Review
- Seasonality and selective trends in viral acute respiratory tract infections.Medical hypotheses · 2016Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRespiratory tract viral infection is one of the most common and important diseases in children. Polymerase chain reaction (PCR) tests are often used to detect viruses in samples, it is difficult to interpret the clinical significance of PCR positivity, which may reflect a past, imminent or active asymptomatic infection due to their high sensitivity. Although single respiratory viruses have been detected in samples from children with symptoms, other respiratory viruses can also be detected simultaneously. However, the clinical importance of these findings for the symptoms is not known.
objectivesTo investigate the prevalence of respiratory viruses among children without any symptoms such as acute respiratory illness and/or fever. STUDY
designFrom week twenty-five 2013 to week twenty-six 2014, gargle samples were collected from children once a week and these samples were subjected to real-time PCR to detect respiratory viruses. On each sampling day, we asked the parents about their children's health condition.
resultsAmong the 286 samples collected, 200 were from asymptomatic children. In the asymptomatic condition, human parechovirus, adenovirus, enterovirus, rhinovirus, coronavirus 229E and HKU1 were observed in 45 episodes. In samples from symptomatic children, parainfluenza viruses, respiratory syncytial virus and coronavirus OC43 were detected in addition to those mentioned above.
conclusionsVarious viruses of different species were detected in the specimens from the children regardless of their health status. It might be speculated that host factors such as the function of the immune system influence the clinical outcome of the infection. However, this needs to be studied further.
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