ArticleScientific reports2015
Using visual lateralization to model learning and memory in zebrafish larvae.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Teleosts as behaviour test models for social stress.Frontiers in behavioral neuroscience · 2023Review
- Learning and memory formation in zebrafish: Protein dynamics and molecular tools.Frontiers in cell and developmental biology · 2023Review
- Article
- A Mini-Review Regarding the Modalities to Study Neurodevelopmental Disorders-Like Impairments in Zebrafish-Focussing on Neurobehavioural and Psychological Responses.Brain sciences · 2022Review
- Glutamate NMDA Receptor Antagonists with Relevance to Schizophrenia: A Review of Zebrafish Behavioral Studies.Current neuropharmacology · 2022Review
- Standardizing Zebrafish Behavioral Paradigms Across Life Stages: An Effort Towards Translational Pharmacology.Frontiers in pharmacology · 2022Review
- Potential Novel Therapies for Neurodevelopmental Diseases Targeting Oxidative Stress.Oxidative medicine and cellular longevity · 2021Review
- Brain and Behavioral Asymmetry: A Lesson From Fish.Frontiers in neuroanatomy · 2020Review
- Zebrafish (Danio rerio) behavioral laterality predicts increased short-term avoidance memory but not stress-reactivity responses.Animal cognition · 2019Article
- Imaging Neuronal Activity in the Optic Tectum of Late Stage Larval Zebrafish.Journal of developmental biology · 2018Article
- Long-term habituation of the C-start escape response in zebrafish larvae.Neurobiology of learning and memory · 2016Article
- Lactobacillus plantarum attenuates anxiety-related behavior and protects against stress-induced dysbiosis in adult zebrafish.Scientific reports · 2016Article
- Microbial modulation of behavior and stress responses in zebrafish larvae.Behavioural brain research · 2016Article
- Spontaneous object recognition: a promising approach to the comparative study of memory.Frontiers in behavioral neuroscience · 2015Review
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Authors and funding
3 authors.
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Abstract
Impaired learning and memory are common symptoms of neurodegenerative and neuropsychiatric diseases. Present, there are several behavioural test employed to assess cognitive functions in animal models, including the frequently used novel object recognition (NOR) test. However, although atypical functional brain lateralization has been associated with neuropsychiatric conditions, spanning from schizophrenia to autism, few animal models are available to study this phenomenon in learning and memory deficits. Here we present a visual lateralization NOR model (VLNOR) in zebrafish larvae as an assay that combines brain lateralization and NOR. In zebrafish larvae, learning and memory are generally assessed by habituation, sensitization, or conditioning paradigms, which are all representatives of nondeclarative memory. The VLNOR is the first model for zebrafish larvae that studies a memory similar to the declarative memory described for mammals. We demonstrate that VLNOR can be used to study memory formation, storage, and recall of novel objects, both short and long term, in 10-day-old zebrafish. Furthermore we show that the VLNOR model can be used to study chemical modulation of memory formation and maintenance using dizocilpine (MK-801), a frequently used non-competitive antagonist of the NMDA receptor, used to test putative antipsychotics in animal models.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.