ArticleMolecular plant pathology2015
Effector discovery in the fungal wheat pathogen Zymoseptoria tritici.
Article in Molecular plant pathology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
38 citing papers in PubMed.
- What makes a mycoparasite? Candidate effectors from fungi that parasitize other fungi exhibit structural homology to those of fungal plant pathogens.Fungal biology and biotechnology · 2026Article
- Optical coherence tomography for early detection of crop infection.Plant methods · 2025Article
- Genome-wide characterization of effector proteins in Fusarium zanthoxyli and their effects on plant's innate immunity responses.BMC plant biology · 2025Article
- Advances in the molecular mechanism of grapevine resistance to fungal diseases.Molecular horticulture · 2025Review
- An array of Zymoseptoria tritici effectors suppress plant immune responses.Molecular plant pathology · 2024Article
- Life on a leaf: the epiphyte to pathogen continuum and interplay in the phyllosphere.BMC biology · 2024Review
- Genome sequencing and comparative genomics reveal insights into pathogenicity and evolution of Fusarium zanthoxyli, the causal agent of stem canker in prickly ash.BMC genomics · 2024Article
- The Egyptian wheat cultivar Gemmeiza-12 is a source of resistance against the fungus Zymoseptoria tritici.BMC plant biology · 2024Article
- Quantitative pathogenicity and host adaptation in a fungal plant pathogen revealed by whole-genome sequencing.Nature communications · 2024Article
- Article
- Quantitative and qualitative plant-pathogen interactions call upon similar pathogenicity genes with a spectrum of effects.Frontiers in plant science · 2023Article
- Rapid sequence evolution driven by transposable elements at a virulence locus in a fungal wheat pathogen.BMC genomics · 2021Article
- Asynchronous development of Zymoseptoria tritici infection in wheat.Fungal genetics and biology : FG & B · 2021Article
- The transcription factor Zt107320 affects the dimorphic switch, growth and virulence of the fungal wheat pathogen Zymoseptoria tritici.Molecular plant pathology · 2020Article
- Characterization of ThreeFrontiers in plant science · 2020Article
- Extracellular vesicles from the apoplastic fungal wheat pathogenFungal biology and biotechnology · 2020Article
- Wheat Encodes Small, Secreted Proteins That Contribute to Resistance to Septoria Tritici Blotch.Frontiers in genetics · 2020Article
- Serpins: Genome-Wide Characterisation and Expression Analysis of the Serine Protease Inhibitor Family inG3 (Bethesda, Md.) · 2019Article
- A small secreted protein triggers a TLR2/4-dependent inflammatory response during invasive Candida albicans infection.Nature communications · 2019Article
- Gene regulation of Sclerotinia sclerotiorum during infection of Glycine max: on the road to pathogenesis.BMC genomics · 2019Article
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fungal plant pathogens, such as Zymoseptoria tritici (formerly known as Mycosphaerella graminicola), secrete repertoires of effectors to facilitate infection or trigger host defence mechanisms. The discovery and functional characterization of effectors provides valuable knowledge that can contribute to the design of new and effective disease management strategies. Here, we combined bioinformatics approaches with expression profiling during pathogenesis to identify candidate effectors of Z. tritici. In addition, a genetic approach was conducted to map quantitative trait loci (QTLs) carrying putative effectors, enabling the validation of both complementary strategies for effector discovery. In planta expression profiling revealed that candidate effectors were up-regulated in successive waves corresponding to consecutive stages of pathogenesis, contrary to candidates identified by QTL mapping that were, overall, expressed at low levels. Functional analyses of two top candidate effectors (SSP15 and SSP18) showed their dispensability for Z. tritici pathogenesis. These analyses reveal that generally adopted criteria, such as protein size, cysteine residues and expression during pathogenesis, may preclude an unbiased effector discovery. Indeed, genetic mapping of genomic regions involved in specificity render alternative effector candidates that do not match the aforementioned criteria, but should nevertheless be considered as promising new leads for effectors that are crucial for the Z. tritici-wheat pathosystem.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.