ArticleCurrent protocols in mouse biology2015
Mouse models of bone healing: fracture, marrow ablation, and distraction osteogenesis.
Article in Current protocols in mouse biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- Maladaptive immune-fibrotic axis drives impaired long bone regeneration under mechanical instability.Science advances · 2026Article
- Enabling adenosine signaling to promote aged fracture healing.NPJ Regenerative medicine · 2025Article
- Improved Methodology for Studying Postnatal Osteogenesis via Intramembranous Ossification in a Murine Bone Marrow Injury Model.Journal of visualized experiments : JoVE · 2025Article
- Improved Methodology for Studying Postnatal Osteogenesis via Intramembranous Ossification in a Murine Bone Marrow Injury Model.bioRxiv : the preprint server for biology · 2024Article
- Article
- Callus γδ T cells and microbe-induced intestinal Th17 cells improve fracture healing in mice.The Journal of clinical investigation · 2023Article
- Prx1 cell subpopulations identified in various tissues with diverse quiescence and activation ability following fracture and BMP2 stimulation.Frontiers in physiology · 2023Article
- Activation of canonical Wnt signaling accelerates intramembranous bone regeneration in male mice.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2022Article
- Post natal expression of Prx1 labels appendicular restricted progenitor cell populations of multiple tissues.Journal of cellular physiology · 2022Article
- Hydrogel as a Biomaterial for Bone Tissue Engineering: A Review.Nanomaterials (Basel, Switzerland) · 2020Review
- Aptamer-Functionalized Fibrin Hydrogel Improves Vascular Endothelial Growth Factor Release Kinetics and Enhances Angiogenesis and Osteogenesis in Critically Sized Cranial Defects.ACS biomaterials science & engineering · 2019Article
- Hypophosphatemia Regulates Molecular Mechanisms of Circadian Rhythm.Scientific reports · 2018Article
- The Generation of Closed Femoral Fractures in Mice: A Model to Study Bone Healing.Journal of visualized experiments : JoVE · 2018Article
- Intramembranous bone regeneration and implant placement using mechanical femoral marrow ablation: rodent models.BoneKEy reports · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Three commonly used murine surgical models of bone healing [closed fracture with intramedullary fixation, distraction osteogenesis (DO), and marrow ablation by reaming] are presented. Detailed surgical protocols for each model are outlined. The nature of the regenerative processes and the types of research questions that may be addressed with these models are briefly outlined. The relative strengths and weaknesses of these models are compared to a number of other surgical models that are used to address similar research questions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.