Evidence map›Paper›PMID 25727123›Full record

Trial reportPsychiatric services (Washington, D.C.)2015

When "need plus supply" does not equal demand: challenges in uptake of depression treatment in HIV clinical care.

Brian W Pence, E Byrd Quinlivan, Amy Heine, Malaika Edwards, Nathan M Thielman, Bradley N Gaynes

Registry-linked trialAbstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Psychiatric services (Washington, D.C.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01372605 (SLAM DUNC), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01372605 nacompletednot on this map

SLAM DUNC: Strategies to Link Antidepressant and Antiretroviral Management at Duke University, University of Alabama at Birmingham, Northern Outreach Clinic (Henderson, NC), and University of North Carolina

TypeinterventionalSponsorDuke UniversityRan2010 to 2014Enrolled304ConditionsDepression, HIVArmsMeasurement-Based Care collaborative depression management, Enhanced Usual Care
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Brian W PenceDr. Pence is with the Department of Epidemiology, University of North Carolina, Chapel Hill (e-mail: bpence@unc.edu ). Dr. Quinlivan, Ms. Heine, and Ms. Edwards are with the Department of Infectious Diseases and Dr. Gaynes is with the Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill. Dr. Thielman is with the Department of Medicine, Duke University, Durham, North Carolina.
E Byrd Quinlivan
Amy Heine
Malaika Edwards
Nathan M Thielman
Bradley N Gaynes

Funding

Virology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9M
Social and Behavioral Sciences CoreP30AI064518 · NIAID · DUKE UNIVERSITY · PI Nwora Lance Okeke · 2005 to 2026
$50.5M
UNC CLINICAL AND TRANSLATIONAL SCIENCE AWARD: BPCAUL1RR025747 · NCRR · UNIV OF NORTH CAROLINA CHAPEL HILL · PI RUNGE, MARSCHALL S. · 2008 to 2011
$44.6M
HIV/AIDS Clinical Trials UnitU01AI069484 · NIAID · DUKE UNIVERSITY · PI BARTLETT, JOHN A · 2007 to 2011
$14.6M
UNC Clinical Translation Science Award-K12 Scholars Program (KL2)KL2RR025746 · NCRR · UNIV OF NORTH CAROLINA CHAPEL HILL · PI RUNGE, MARSCHALL S. · 2008 to 2011
$9.0M
Improving HAART Adherence in Depressed HIV Clinic Patients: A Real-World RCTR01MH086362 · NIMH · DUKE UNIVERSITY · PI PENCE, BRIAN W · 2009 to 2013
$3.5M
NCRR NIH HHS KL2 RR025746NCRR NIH HHS UL1 RR025747NIAID NIH HHS 2P30 AI064518NIAID NIH HHS P30 AI050410NIAID NIH HHS P30 AI064518NIAID NIH HHS P30 AI50410NIAID NIH HHS U01 AI069484NIMH NIH HHS R01 MH086362
6 · The paper itself

Abstract

objectiveDepression is common among patients in HIV care and is associated with worse HIV-related health behaviors and outcomes. Effective depression treatment is available, yet depression remains widely underdiagnosed and undertreated in HIV care.

methodsAs part of a multisite, randomized trial of depression treatment in HIV clinical care, the proportion of positive depression screens that resulted in study enrollment and reasons for nonenrollment were examined.

resultsOver 33 months, patients completed 9,765 depression screens; 19% were positive for depression, and of these 88% were assessed for study eligibility. Of assessed positive screens, 11% resulted in study enrollment. Nonenrollment after a positive screen was sometimes dictated by the study eligibility criteria, but it was often related to potentially modifiable provider- or patient-level barriers.

conclusionsAddressing patient- and provider-level barriers to engaging in depression treatment will be critical to maximize the reach of depression treatment services for HIV patients.

Indexed as

Depressive DisorderHealth Services Needs and DemandHIV InfectionsHumansPatient Acceptance of Health CareSocioeconomic Factors

Identifiers

PMID25727123
PMCPMC4381922

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.