Evidence map›Paper›PMID 25726934›Full record

ArticleMagnetic resonance in medicine2016

Model predictive filtering MR thermometry: Effects of model inaccuracies, k-space reduction factor, and temperature increase rate.

Henrik Odéen, Nick Todd, Christopher Dillon, Allison Payne, Dennis L Parker

Open access · bronzeAbstract read
In one paragraph

Article in Magnetic resonance in medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Integrating temperature-dependent tissue properties into focused ultrasound computational models for enhanced treatment planning.International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Henrik OdéenDepartment of Radiology, University of Utah, Salt Lake City, Utah, USA.
Nick ToddDepartment of Radiology, University of Utah, Salt Lake City, Utah, USA.
Christopher DillonDepartment of Bioengineering, University of Utah, Salt Lake City, Utah, USA.
Allison PayneDepartment of Radiology, University of Utah, Salt Lake City, Utah, USA.
Dennis L ParkerDepartment of Radiology, University of Utah, Salt Lake City, Utah, USA.
University of Utah · US

Funding

Non-Invasive MRI-Guided HIFU for Breast Cancer TherapyR01CA172787 · NCI · UNIVERSITY OF UTAH · PI PARKER, DENNIS L · 2013 to 2017
$2.7M
Non-Invasive Image-Guided HIFU for Breast Cancer TherapyR01CA134599 · NCI · UNIVERSITY OF UTAH · PI PARKER, DENNIS L, ROEMER, ROBERT · 2008 to 2011
$2.4M
Improved MRI temperature imaging using a subject-specific biophysical modelR01EB013433 · NIBIB · UNIVERSITY OF UTAH · PI PARKER, DENNIS L · 2011 to 2014
$1.8M
The role of T2 and blood flow properties in MRgFUS treatments of uterine fibroidsF32HD085685 · NICHD · UNIVERSITY OF UTAH · PI DILLON, CHRISTOPHER R · 2015 to 2017
$137k
MR Temperature Measurements in Fat During MR-Guided HIFU TreatmentsF32EB012917 · NIBIB · UNIVERSITY OF UTAH · PI TODD, NICHOLAS E. · 2011 to 2012
$96k
NCI NIH HHS CA134599NCI NIH HHS CA172787NCI NIH HHS R01 CA134599NCI NIH HHS R01 CA172787NIBIB NIH HHS F32 EB012917NIBIB NIH HHS F32 EB012917-02NIBIB NIH HHS R01 EB013433NICHD NIH HHS F32 HD085685PHS HHS R01SEB013433
6 · The paper itself

Abstract

purposeEvaluate effects of model parameter inaccuracies (thermal conductivity, k, and ultrasound power deposition density, Q), k-space reduction factor (R), and rate of temperature increase ( T˙) in a thermal model-based reconstruction for MR-thermometry during focused-ultrasound heating.

methodsSimulations and ex vivo experiments were performed to investigate the accuracy of the thermal model and the model predictive filtering (MPF) algorithm for varying R and T˙, and their sensitivity to errors in k and Q. Ex vivo data was acquired with a segmented EPI pulse sequence to achieve large field-of-view (192 × 162 × 96 mm) four-dimensional temperature maps with high spatiotemporal resolution (1.5 × 1.5 × 2.0 mm, 1.7 s).

resultsIn the simulations, 50% errors in k and Q resulted in maximum temperature root mean square errors (RMSE) of 6 °C for model only and 3 °C for MPF. Using recently developed methods, estimates of k and Q were accurate to within 3%. The RMSE between MPF and true temperature increased with R and T˙. In the ex vivo study the RMSE remained below 0.7 °C for R ranging from 4 to 12 and T˙ of 0.28-0.75 °C/s.

conclusionErrors in MPF temperatures occur due to errors in k and Q. These MPF temperature errors increase with increase in R and T˙, but are smaller than those obtained using the thermal model alone.

Indexed as

Models, BiologicalBody TemperatureComputer SimulationHigh-Energy Shock WavesHigh-Intensity Focused Ultrasound AblationMagnetic Resonance ImagingMuscle, SkeletalReproducibility of ResultsSensitivity and SpecificitySignal Processing, Computer-AssistedSurgery, Computer-AssistedTemperatureThermographyHIFUMPFMR thermometryMRTIPRF

Identifiers

PMID25726934
PMCPMC4549212
OpenAlexW1961117953

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.