ArticleJournal of gastroenterology2015
Clinical usefulness of endocytoscopy in the remission stage of ulcerative colitis: a pilot study.
Article in Journal of gastroenterology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- Incremental Benefit of Achieving Endoscopic and Histologic Remission in Patients With Ulcerative Colitis: A Systematic Review and Meta-Analysis.Gastroenterology · 2020Pooled it
- Histological Disease Activity as a Predictor of Clinical Relapse Among Patients With Ulcerative Colitis: Systematic Review and Meta-Analysis.The American journal of gastroenterology · 2016Pooled it
- Endocytoscopy in real-time assessment of histological and endoscopic activity in ulcerative colitis.World journal of gastrointestinal endoscopy · 2025Article
- Review
- Present and future of endoscopy precision for inflammatory bowel disease.Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2024Review
- Public Imaging Datasets of Gastrointestinal Endoscopy for Artificial Intelligence: a Review.Journal of digital imaging · 2023Review
- Next-Generation Endoscopy in Inflammatory Bowel Disease.Diagnostics (Basel, Switzerland) · 2023Review
- Ultra-high Magnification Endocytoscopy and Molecular Markers for Defining Endoscopic and Histologic Remission in Ulcerative Colitis-An Exploratory Study to Define Deep Remission.Inflammatory bowel diseases · 2021Article
- Application of artificial intelligence in gastrointestinal disease: a narrative review.Annals of translational medicine · 2021Review
- Clinical Efficacy of Endocytoscopy for Gastrointestinal Endoscopy.Clinical endoscopy · 2021Article
- Clinical usefulness of linked color imaging for evaluation of endoscopic activity and prediction of relapse in ulcerative colitis.International journal of colorectal disease · 2021Article
- NLRP3 inflammasome has a protective effect against oxazolone-induced colitis: a possible role in ulcerative colitis.Scientific reports · 2016Article
- Application and Efficacy of Super-Magnifying Endoscopy for the Lower Intestinal Tract.Clinical endoscopy · 2016Review
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHistopathology can be used to detect ulcerative colitis (UC) relapse, but diagnosis of the disease activity by histopathology requires multiple biopsies to be taken. Magnifying endocytoscopy provides a method for real-time ultra-magnifying imaging. It was recently reported that the endocytoscopy system score (ECSS) correlates well with the histopathology of UC. Here we evaluated the clinical usefulness of endocytoscopy for accurately monitoring UC during remission.
methodsWe performed endocytoscopy on 26 patients with UC in remission that had been diagnosed by conventional colonoscopy at our institution between January and April 2013. Endocytoscopy was performed at the area of the rectum where UC had been detected with conventional endoscopy. Biopsies were also taken from the same area and histopathology was evaluated by a single pathologist according to the Matts' grading system. The correlation between the relapse rate of UC and both the ECSS and the Matts' histopathological grade was evaluated.
resultsThe ECSS of the intestinal mucosa in UC showed a correlation with the Matts' histopathological grade (Spearman's |r| = 0.647). The patients were classified into two groups: those with an ECSS of 0-2 (Grade A, 12 cases) and those with an ECSS of 3-6 (Grade B, 10 cases). To date, three Grade B cases have relapsed and no Grade A cases have relapsed. The average post-endocytoscopy surveillance period was 446 ± 92 days.
conclusionsThe ECSS may be a predictive indicator for UC relapse since there was a correlation between the ECSS and the degree of inflammation as determined by histopathology.
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