ArticleMolecular biology and evolution2015
Sphingolipids, Transcription Factors, and Conserved Toolkit Genes: Developmental Plasticity in the Ant Cardiocondyla obscurior.
Article in Molecular biology and evolution, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Fitness related effects of titanium dioxide nanoparticles and glyphosate exposure on Cardiocondyla obscurior.Environmental science and pollution research international · 2026Article
- Comparative analysis of 163 ant genomes reveals recurrent horizontal gene transfer from bacteria to ants.GigaScience · 2026Article
- Insect Lipids: Structure, Classification and Function.Advances in experimental medicine and biology · 2026Review
- Exploring the genetics of social behaviour in C. calcarata.Scientific reports · 2025Article
- Causes and consequences of a complex recombinational landscape in the antGenome research · 2024Article
- Sex- and caste-specific developmental responses to juvenile hormone in an ant with maternal caste determination.The Journal of experimental biology · 2024Article
- A Mediator subunit imparts robustness to a polyphenism decision.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Canalized gene expression during development mediates caste differentiation in ants.Nature ecology & evolution · 2022Article
- Article
- A molecular toolkit for superorganisms.Trends in genetics : TIG · 2021Review
- Identification and Expression Profiling of Peripheral Olfactory Genes in the Parasitoid WaspInsects · 2019Article
- Rate variation in the evolution of non-coding DNA associated with social evolution in bees.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2019Article
- Transcriptomic changes during caste development through social interactions in the termiteEcology and evolution · 2019Article
- De novo transcriptome assembly and its annotation for the black ant Formica fusca at the larval stage.Scientific data · 2018Article
- Queen Control or Queen Signal in Ants: What Remains of the Controversy 25 Years After Keller and Nonacs' Seminal Paper?Journal of chemical ecology · 2018Review
- Building a new research framework for social evolution: intralocus caste antagonism.Biological reviews of the Cambridge Philosophical Society · 2018Review
- MicroRNAs Associated with Caste Determination and Differentiation in a Primitively Eusocial Insect.Scientific reports · 2017Article
- Life-history evolution in ants: the case ofProceedings. Biological sciences · 2017Review
- Accelerated Evolution of Developmentally Biased Genes in the Tetraphenic Ant Cardiocondyla obscurior.Molecular biology and evolution · 2017Article
- On the Molecular Basis of Division of Labor in Solenopsis invicta (Hymenoptera: Formicidae) Workers: RNA-seq Analysis.Journal of insect science (Online) · 2017Article
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4 authors.
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Abstract
Developmental plasticity allows for the remarkable morphological specialization of individuals into castes in eusocial species of Hymenoptera. Developmental trajectories that lead to alternative caste fates are typically determined by specific environmental stimuli that induce larvae to express and maintain distinct gene expression patterns. Although most eusocial species express two castes, queens and workers, the ant Cardiocondyla obscurior expresses diphenic females and males; this provides a unique system with four discrete phenotypes to study the genomic basis of developmental plasticity in ants. We sequenced and analyzed the transcriptomes of 28 individual C. obscurior larvae of known developmental trajectory, providing the first in-depth analysis of gene expression in eusocial insect larvae. Clustering and transcription factor binding site analyses revealed that different transcription factors and functionally distinct sets of genes are recruited during larval development to induce the four alternative trajectories. In particular, we found complex patterns of gene regulation pertaining to sphingolipid metabolism, a conserved molecular pathway involved in development, obesity, and aging.
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