Evidence map›Paper›PMID 2572508›Full record

ArticleGenetics1989

A molecular genetic linkage map of mouse chromosome 9 with regional localizations for the Gsta, T3g, Ets-1 and Ldlr loci.

D M Kingsley, N A Jenkins, N G Copeland

Abstract read
In one paragraph

Article in Genetics, 1989. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. X-ray-induced deletion complexes in embryonic stem cells on mouse chromosome 15.Mammalian genome : official journal of the International Mammalian Genome Society · 2005
    Article
  2. Article
  3. Characterization of human crossover interference.American journal of human genetics · 2000
    Article
  4. Mapping the mouse genome: current status and future prospects.Proceedings of the National Academy of Sciences of the United States of America · 1995
    Review
  5. Article
  6. Article
  7. Article
  8. Mouse chromosome 9.Mammalian genome : official journal of the International Mammalian Genome Society · 1992
    Review
  9. Comparative map for mice and humans.Mammalian genome : official journal of the International Mammalian Genome Society · 1992
    Review
  10. Article
  11. Article
  12. Article
  13. Ras-like genes and gene families in the mouse.Mammalian genome : official journal of the International Mammalian Genome Society · 1991
    Article
  14. Meiotic mapping of murine chromosome 17: the string of loci around l(17)-2Pas.Mammalian genome : official journal of the International Mammalian Genome Society · 1991
    Article
  15. Mouse chromosome 9.Mammalian genome : official journal of the International Mammalian Genome Society · 1991
    Review
  16. Mouse map of paralogous genes.Mammalian genome : official journal of the International Mammalian Genome Society · 1991
    Review
  17. Comparative map for mice and humans.Mammalian genome : official journal of the International Mammalian Genome Society · 1991
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

D M KingsleyMammalian Genetics Laboratory, NCI-Frederick Cancer Research Facility, Maryland 21701.
N A Jenkins
N G Copeland

Funding

PROVIDE BASIC CANCER RESEARCHN01CO074101 · CO · ADVANCED BIOSCIENCE LABORATORIES, INC. · PI VANDE WOUDE, GEORGE F · 1987 to 1994
–
NCI NIH HHS N01-CO-74101
6 · The paper itself

Abstract

A 64-centiMorgan linkage map of mouse chromosome 9 was developed using cloned DNA markers and an interspecific backcross between Mus spretus and the C57BL/6J inbred strain. This map was compared to conventional genetic maps using six markers previously localized in laboratory mouse strains. These markers included thymus cell antigen-1, cytochrome P450-3, dilute, transferrin, cholecystokinin, and the G-protein alpha inhibitory subunit. No evidence was seen for segregation distortion, chromosome rearrangements, or altered genetic distances in the results from interspecific backcross mapping. Regional map locations were determined for four genes that were previously assigned to chromosome 9 using somatic cell hybrids. These genes were glutathione S-transferase Ya subunit (Gsta), the T3 gamma subunit, the low density lipoprotein receptor, and the Ets-1 oncogene. The map locations for these genes establish new regions of synteny between mouse chromosome 9 and human chromosomes 6, 11, and 19. In addition, the close linkage detected between the dilute and Gsta loci suggests that the Gsta locus may be part of the dilute/short ear complex, one of the most extensively studied genetic regions of the mouse.

Indexed as

Chromosome MappingGenetic LinkageAnimalsGenetic MarkersMicePolymorphism, Restriction Fragment LengthRecombination, GeneticGenetic Markers

Identifiers

PMID2572508
PMCPMC1203779

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.