Evidence map›Paper›PMID 25724967›Full record

Observational studyTechniques in coloproctology2015

Fistula-tract Laser Closure (FiLaC™): long-term results and new operative strategies.

P Giamundo, L Esercizio, M Geraci, L Tibaldi, M Valente

3 registry-linked trialsAbstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Techniques in coloproctology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 52 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03017898 nasuspendednot on this mapstarted 2017, after this paper: background citation

Treatment of Anal Fistula With Laser Mediated Heat Coagulation Using Fistula Laser Closure (FiLaC)

TypeinterventionalSponsorRegion SkaneRan2017 to 2025Enrolled52ConditionsFistula-In-Ano, Anal FistulaArmsLaser Coagulation
NCT04508374 naunknown statusnot on this mapstarted 2020, after this paper: background citation

Intralesional Diode Laser Treatment of Fistulas in Hidradenitis Suppurativa: Protocol for a Within-person Randomised Trial

TypeinterventionalSponsorZealand University HospitalRan2020 to 2025Enrolled20ConditionsHidradenitis SuppurativaArms1470 nm intra-lesional diode laser treatment of right HS tunnel, 1470 nm intra-lesional diode laser treatment of left HS tunnel
NCT05201209 completednot on this mapstarted 2019, after this paper: background citation

LASER FiLaC™ (FISTULA LASER CLOSURE) : First-line Treatment of Complex Anal Fistulas

TypeobservationalSponsorFondation Hôpital Saint-JosephRan2019 to 2019Enrolled110ConditionsComplex Anal Fistula
3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 7 syntheses or guidelines pooled it.

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  10. Outcomes of Transanal Advancement Flap Repair and Hybrid Seton Placement in 84 Patients With Transsphincteric Anal Fistula.Medical science monitor : international medical journal of experimental and clinical research · 2026
    Article
  11. Ligation of the intersphincteric fistula tractWorld journal of gastrointestinal surgery · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

P GiamundoDepartment of General Surgery, S. Spirito Hospital, Bra, CN, Italy, pgiamundo@gmail.com.
L Esercizio
M Geraci
L Tibaldi
M Valente

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFistula-tract Laser Closure (FiLaC™) is a sphincter-saving technique for the treatment of anal fistulas that has been shown to be successful in the short and middle term. However, the long-term success rate is unknown. This study aimed to report long-term results in performing FiLaC™.

methodsThis study was performed as a retrospective observational study. Forty-five patients who underwent FiLaC™ between July 2010 and May 2014 were evaluated. In all cases, FiLaC™ was performed with a diode laser at a wavelength of 1470 nm by means of a radial fiber. Patients and fistula characteristics, previous treatments, healing rates, failures and postoperative incontinence were reviewed.

resultsMedian follow-up time was 30 months (range 6-46 months). Thirty-five patients (78%) had a history of previous surgery for their fistulas. Primary healing was observed in 32 patients (71.1%), and the median healing time was 5 weeks (range 3-8 weeks). Eleven of the 13 failures (85%) were early failures (persistent symptoms). No patient reported postoperative incontinence. The best healing rate was observed in patients who had been previously treated with loose seton (19/24, 79%).

conclusionsLong-term follow-up after FiLaC™ seems to confirm the favorable short-term success rates reported for this procedure. Although sealing of chronic anal fistulas may be obtained with FiLaC™ in a single treatment, our current strategy consists of placing a loose seton into the fistula tract a few weeks prior to laser treatment. Seton treatment facilitates the following laser procedure and seems to have favorable effects on healing.

Indexed as

AdolescentAdultAgedAnal CanalFemaleFollow-Up StudiesHumansLaser TherapyMaleMiddle AgedPostoperative ComplicationsRectal FistulaRetrospective StudiesSurvival AnalysisTreatment OutcomeWound Healing

Identifiers

What OpenQuestion holds

Textmetadata
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.