Evidence map›Paper›PMID 25724853›Full record

ArticleDiagnostic microbiology and infectious disease2015

Comparison of the performance of 2 commercial multiplex PCR platforms for detection of respiratory viruses in upper and lower tract respiratory specimens.

Elisa Costa, Mario Rodríguez-Domínguez, María Ángeles Clari, Estela Giménez, Juan Carlos Galán, David Navarro

Open access · greenAbstract readComparative StudyEvaluation Study
In one paragraph

Article in Diagnostic microbiology and infectious disease, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Role of Human Bocavirus Respiratory Tract Infection in Hematopoietic Cell Transplant Recipients.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021
    Article
  3. Clinical Effectiveness of Influenza Vaccination After Allogeneic Hematopoietic Stem Cell Transplantation: A Cross-sectional, Prospective, Observational Study.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2019
    Observational
  4. Article
  5. Article
  6. Observational
  7. Epidemiologic and Clinical Characteristics of Coronavirus and Bocavirus Respiratory Infections after Allogeneic Stem Cell Transplantation: A Prospective Single-Center Study.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation · 2018
    Article
  8. Article
  9. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Elisa CostaServicio de Microbiología, Hospital Clínico Universitario, Fundación INCLIVA, Valencia, Spain.
Mario Rodríguez-DomínguezServicio de Microbiología, Hospital Ramón y Cajal, and Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain; Red Española para la Investigación en Enfermedades Infecciosas (REIPI), Madrid, Spain.
María Ángeles ClariServicio de Microbiología, Hospital Clínico Universitario, Fundación INCLIVA, Valencia, Spain.
Estela GiménezServicio de Microbiología, Hospital Clínico Universitario, Fundación INCLIVA, Valencia, Spain.
Juan Carlos GalánServicio de Microbiología, Hospital Ramón y Cajal, and Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain; CIBER en Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.
David NavarroServicio de Microbiología, Hospital Clínico Universitario, Fundación INCLIVA, Valencia, Spain; Department of Microbiology, School of Medicine, University of Valencia, Valencia, Spain. Electronic address: david.navarro@uv.es.
Instituto Ramón y Cajal de Investigación Sanitaria · ESRed Espanola de Investigacion en Patologia Infecciosa · ESUniversitat de València · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The performance of the CLART® PneumoVir system with that of the Luminex xTAG RVP Fast v1 assay for detection of most common respiratory viruses in upper and lower tract respiratory specimens (n=183) from unique patients with influenza-like syndrome or lower tract respiratory infection. Nested PCR coupled to automated sequencing was used for resolution of discrepancies. Fully concordant results were obtained for a total of 122 specimens, whereas 56 specimens gave partially (n=21) or fully discordant (n=35) results (Kappa coefficient, 0.62). The overall specificity of the Luminex xTAG RVP Fast v1 assay was slightly higher than that of the CLART® PneumoVir assay for human bocavirus, influenza A virus/H3N2, influenza B virus, human metapneumovirus, and parainfluenza virus, whereas the sensitivity of the latter was higher for most targeted viruses except, notably, for picornaviruses. This was irrespective of either the origin of the respiratory specimen or the age group to which the patients belonged.

Indexed as

AdolescentAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedMultiplex Polymerase Chain ReactionRespiratory SystemRespiratory Tract InfectionsRetrospective StudiesSensitivity and SpecificityVirus DiseasesVirusesYoung AdultAcute respiratory tract infectionMultiplex PCRRespiratory viruses

Identifiers

PMID25724853
PMCPMC7132747
OpenAlexW2143567799

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.