Evidence map›Paper›PMID 25724830›Full record

ArticleAnnals of epidemiology2015

Female and male differences in AIDS diagnosis rates among people who inject drugs in large U.S. metro areas from 1993 to 2007.

Brooke S West, Enrique R Pouget, Barbara Tempalski, Hannah L F Cooper, H Irene Hall, Xiaohong Hu, Samuel R Friedman

Open access · greenAbstract read
In one paragraph

Article in Annals of epidemiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Brooke S WestDivision of Global Public Health, School of Medicine, University of California, San Diego, La Jolla, CA. Electronic address: bswest@ucsd.edu.
Enrique R PougetNational Development and Research Institutes, Inc., New York, NY.
Barbara TempalskiNational Development and Research Institutes, Inc., New York, NY.
Hannah L F CooperDepartment of Behavioral Sciences and Health Education, Rollins School of Public Health, Emory University, Atlanta, GA.
H Irene HallCenters for Disease Control and Prevention, Atlanta, GA.
Xiaohong HuCenters for Disease Control and Prevention, Atlanta, GA.
Samuel R FriedmanNational Development and Research Institutes, Inc., New York, NY.
National Development and Research Institutes · USCenters for Disease Control and Prevention · USEmory University · USUniversity of California San Diego · US

Funding

Transdisciplinary Theoretical Svnthesis and Development CoreP30DA011041 · NIDA · NEW YORK UNIVERSITY · PI Holly Hagan, Courtney McKnight · 1998 to 2026
$38.9M
Training Program in Substance Use, HIV and Related InfectionsT32DA023356 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Natasha Martin, Steffanie A Strathdee · 2007 to 2026
$7.8M
COMMUNITY VULNERABILITY AND RESPONSES TO IDU-RELATED HIVR01DA013336 · NIDA · NATIONAL DEVELOPMENT &RES INSTITUTES · PI COOPER, HANNAH LF, FRIEDMAN, SAMUEL R · 2000 to 2013
$7.6M
Metropolitan Trajectories of HIV Epidemics, Drug Use, and Responses in US Key PopulationsR01DA037568 · NIDA · EMORY UNIVERSITY · PI COOPER, HANNAH LF, FRIEDMAN, SAMUEL R · 2014 to 2018
$4.0M
NIDA NIH HHS P30 DA011041NIDA NIH HHS P30 DA121041NIDA NIH HHS R01 DA013336NIDA NIH HHS R01 DA037568NIDA NIH HHS T32 DA023356
6 · The paper itself

Abstract

purposeWe estimated female and male incident AIDS diagnosis rates (IARs) among people who inject drugs (PWID) in U.S. metropolitan statistical areas (MSAs) over time to assess whether declines in IARs varied by sex after combination antiretroviral therapy (cART) dissemination.

methodsWe compared IARs and 95% confidence intervals for female and male PWID in 95 of the most populous MSAs. To stabilize estimates, we aggregated data across three-year periods, selecting a period immediately preceding cART (1993-1995) and the most recent after the introduction of cART for which data were available (2005-2007). We assessed disparities by comparing IAR 95% confidence intervals for overlap, female-to-male risk ratios, and disparity change scores.

resultsIARs declined an average of 58% for female PWID and 67% for male PWID between the pre-cART and cART periods. Among female PWID, IARs were significantly lower in the later period relative to the pre-cART period in 48% of MSAs. Among male PWID, IARs were significantly lower over time in 86% of MSAs.

conclusionsIARs among female PWID in large U.S. MSAs have declined more slowly than among male PWID. This suggests a need for increased targeting of prevention and treatment programs and for research on MSA level conditions that may drive differences in declining AIDS rates among female and male PWID.

Indexed as

AdolescentAdultAnti-HIV AgentsFemaleHIV InfectionsHumansIncidenceMaleMiddle AgedRetrospective StudiesSex FactorsSubstance Abuse, IntravenousUnited StatesUrban PopulationYoung AdultAnti-HIV AgentsAIDSGenderHealth status disparitiesInjection drug use

Identifiers

PMID25724830
PMCPMC4470700
OpenAlexW2163024788

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.