ArticlePsychopharmacology2015
Discrepant effects of acute cocaine on impulsive choice (delay discounting) in female rats during an increasing- and adjusting-delay procedure.
Article in Psychopharmacology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed, 14 citations in OpenAlex.
- Methylphenidate reduces rats' temporal discounting of aversive outcomes.Psychopharmacology · 2026Article
- Selective chemogenetic inactivation of corticoaccumbal projections disrupts trait choice impulsivity.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2023Article
- Impaired delay discounting and time sensitivity in methcathinone use disorder.European archives of psychiatry and clinical neuroscience · 2022Article
- The synthetic cathinone 3,4-methylenedioxypyrovalerone increases impulsive action in rats.Behavioural pharmacology · 2020Article
- Repeated administration of synthetic cathinone 3,4-methylenedioxypyrovalerone persistently increases impulsive choice in rats.Behavioural pharmacology · 2019Article
- Dissecting drug effects in preclinical models of impulsive choice: emphasis on glutamatergic compounds.Psychopharmacology · 2018Review
- Sex-specific attenuation of impulsive action by progesterone in a go/no-go task for cocaine in rats.Psychopharmacology · 2018Article
- Sex differences in the reduction of impulsive choice (delay discounting) for cocaine in rats with atomoxetine and progesterone.Psychopharmacology · 2016Article
- To Act or Not to Act: Endocannabinoid/Dopamine Interactions in Decision-Making.Frontiers in behavioral neuroscience · 2015Review
- Sex Differences in Behavioral Dyscontrol: Role in Drug Addiction and Novel Treatments.Frontiers in psychiatry · 2015Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
rationaleThe relationship between impulsive choice and cocaine use in humans has been well established, although the causal role between these variables is complex. To disentangle this relationship, studies using rats have focused on how acute or chronic cocaine alters impulsive choice. A predominance of studies has focused on chronic cocaine regimens, but few have assessed acute cocaine's effects on impulsive choice.
objectiveThe current study assessed if acute cocaine administrations alter delay discounting of rats in two common impulsive choice procedures.
methodBaseline delay discounting rates were determined in female rats using both an increasing- and adjusting-delay procedure. Once stable, a range of acute cocaine injections (2, 5, and 15 mg/kg i.p.) was administered prior to both procedures.
resultsBaseline delay discounting rates were positively correlated between the increasing- and adjusting-delay procedures. Acute administrations of cocaine produced a dose-dependent decrease in preference for the large alternative in the increasing-delay procedure but had no effect in the adjusting-delay procedure.
conclusionsThe concordance of delay discounting rates across the two choice procedures suggests that both quantify the same underlying components of impulsive choice. However, manipulations that disrupt large alternative preference may not be readily detected under the adjusting-delay procedure unless control conditions are employed.
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