Evidence map›Paper›PMID 25724179›Full record

ReviewExperimental eye research2015

Vitamin D: Implications for ocular disease and therapeutic potential.

Rose Y Reins, Alison M McDermott

Open access · greenAbstract readReview
In one paragraph

Review in Experimental eye research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 1 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 1 synthesis or guideline pooled it, 93 citations in OpenAlex.

  1. Vitamin D and Ocular Diseases: A Systematic Review.International journal of molecular sciences · 2022
    Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Observational
  9. Review
  10. Article
  11. Review
  12. Review
  13. Article
  14. Review
  15. Article
  16. [Serum 25-hydroxyvitamin D expression and its correlation in patients with vestibular neuritis].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2022
    Article
  17. Review
  18. Article
  19. Serum 25-hydroxy vitamin D levels in age-related macular degeneration.International journal of retina and vitreous · 2022
    Article
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Rose Y ReinsThe Ocular Surface Institute, University of Houston College of Optometry, 4901 Calhoun Road, Houston, TX 77204-2020, USA. Electronic address: rose@reins.org.
Alison M McDermottThe Ocular Surface Institute, University of Houston College of Optometry, 4901 Calhoun Road, Houston, TX 77204-2020, USA. Electronic address: AMcdermott@OPTOMETRY.UH.EDU.
University of Houston · US

Funding

Research Programming ModuleP30EY007551 · NEI · UNIVERSITY OF HOUSTON · PI LAURA J. FRISHMAN · 1988 to 2026
$16.4M
Role of Antimicrobial Peptides at the Ocular SurfaceR01EY013175 · NEI · UNIVERSITY OF HOUSTON · PI MCDERMOTT, ALISON M · 2001 to 2016
$4.3M
Training Program with Universitiy of HoustonT32EY007024 · NEI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MASSEY, STEPHEN C · 1987 to 2016
$1.8M
NEI NIH HHS EY13175NEI NIH HHS P30 EY007551NEI NIH HHS R01 EY013175NEI NIH HHS T32 EY007024PHS HHS T32 07024
6 · The paper itself

Abstract

Vitamin D is a multifunctional hormone that is now known to play a significant role in a variety of biological functions in addition to its traditional role in regulating calcium homeostasis. There are a large number of studies demonstrating that adequate vitamin D levels are important in maintaining health and show that vitamin D is able to be utilized at local tissue sites. In the eye, we have increasing evidence of the association between disease and vitamin D. In this narrative review, we summarize recent findings on vitamin D and its relationship to various ocular pathologies and the therapeutic potential for some of these, as well as examine the basic science studies that demonstrate that vitamin D is biologically relevant in the eye.

Indexed as

CalciumEye DiseasesHumansImmune SystemVitamin DVitamin D DeficiencyCalciumVitamin DAnti-inflammatoryDeficiencyGenetic variationsOcular diseaseVitamin D

Identifiers

PMID25724179
PMCPMC4426046
OpenAlexW2095997963

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.