ArticleInflammatory bowel diseases2015
Exercise decreases risk of future active disease in patients with inflammatory bowel disease in remission.
Article in Inflammatory bowel diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05174754 (The Impact Of A Physician-led Exercise Programme On Quality Of Life, Muscle Mass And Clinical Response In Inflammatory Bowel Disease Patients During Induction With Medical Therapy), which is not on this map. Cited by 61 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Impact Of A Physician-led Exercise Programme On Quality Of Life, Muscle Mass And Clinical Response In Inflammatory Bowel Disease Patients During Induction With Medical Therapy
Who cites it
61 citing papers in PubMed, 1 synthesis or guideline pooled it.
- AGA Clinical Practice Update on Functional Gastrointestinal Symptoms in Patients With Inflammatory Bowel Disease: Expert Review.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2019Guideline
- Trial
- Moderate endurance and muscle training is beneficial and safe in patients with quiescent or mildly active Crohn's disease.United European gastroenterology journal · 2020Trial
- Fatigue in Inflammatory Bowel Disease: The Role of Drug Therapy Within a Holistic Management Framework.Drugs · 2026Review
- Lifestyle restrictions are associated with impaired quality of life but not reduction in relapse in ulcerative colitis.Intestinal research · 2026Article
- Psychological distress predicts disease activity in inflammatory bowel disease: Results from the mind-body IBD longitudinal study.Brain, behavior, & immunity - health · 2026Article
- Physical Activity Is Inversely Associated with Clinical Exacerbation in Patients with Crohn's Disease in Remission: A Prospective Cohort Study.Digestive diseases (Basel, Switzerland) · 2026Article
- Physical activity and sedentary behavior patterns in adults with Crohn's disease versus matched controls: accelerometer and self-report findings.Sport sciences for health · 2026Article
- The complex relationship between physical activity and fatigue with socioeconomic status, and mental health factors in individuals with inflammatory bowel disease.Journal of Crohn's & colitis · 2025Article
- Physical Activity and Education in the Care of IBD: The Role of the Physiotherapist-A Narrative Review.Journal of clinical medicine · 2025Review
- Accelerometer-measured moderate-to-vigorous physical activity is associated with reduced risk of bowel resection and mortality in inflammatory bowel disease: a prospective cohort study.International journal of surgery (London, England) · 2025Article
- Association of healthy lifestyle, metabolic alterations and lower mortality risk of IBD patients: a prospective cohort and mediation analysis.Family medicine and community health · 2025Article
- Analysis of exercise behavior and influencing factors in patients with inflammatory bowel disease during remission and mild disease activity.BMC gastroenterology · 2025Article
- Predictors of antitumor necrosis factor primary nonresponse and drug durability in pediatric inflammatory bowel disease.Journal of pediatric gastroenterology and nutrition · 2025Article
- Impaired physical fitness in pediatric inflammatory bowel disease.Journal of pediatric gastroenterology and nutrition · 2025Article
- Patterns and Correlates of Sedentary Behavior and Physical Activity in Individuals With Crohn's Disease: A Cross-Sectional Study.Crohn's & colitis 360 · 2025Article
- Association between adherence to Mediterranean-DASH intervention for neurodegenerative delay diet and disease severity in patients with ulcerative colitis.Scientific reports · 2025Article
- Influence of biological sex in inflammatory bowel diseases.Nature reviews. Gastroenterology & hepatology · 2025Review
- Lifestyle and psychosocial factors in inflammatory bowel disease: Prevalence, impact, motivation, and support needs.PloS one · 2025Article
- Management of Overweight and Obesity in Patients With Inflammatory Bowel Disease.Gastroenterology & hepatology · 2024Article
1 more citing papers are in PubMed but not listed here.
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Authors and funding
6 authors.
Funding
Abstract
backgroundAlthough exercise impacts quality of life in patients with inflammatory bowel disease, little is known about its role in disease activity. Among patients with inflammatory bowel disease in remission, we aimed to evaluate the association between exercise and subsequent active disease.
methodsWe performed a prospective study using the Crohn's and Colitis Foundation of America Partners' internet-based cohort of individuals with self-reported inflammatory bowel disease. We identified participants in remission, defined as short Crohn's disease activity index <150 or simple clinical colitis activity index ≤2. The primary exposure was exercise status, measured using the validated Godin leisure-time activity index. The primary study outcome, assessed after 6 months, was active disease defined using the above disease activity index thresholds. We used bivariate and multivariate analyses to describe the independent association between exercise and risk of active disease.
resultsWe identified 1308 patients with Crohn's disease (CD) and 549 with ulcerative or indeterminate colitis (UC/IC) in remission, of whom 227 (17.4%) with CD and 135 (24.6%) with UC/IC developed active disease after 6 months. Higher exercise level was associated with decreased risk of active disease for CD (adjusted risk ratio: 0.72, 95% confidence interval: 0.55-0.94) and UC/IC (adjusted risk ratio: 0.78, 95% confidence interval: 0.54-1.13).
conclusionsIn patients with CD in remission, those with higher exercise levels were significantly less likely to develop active disease at 6 months. In patients with UC/IC in remission, patients with higher exercise levels were less likely to develop active disease at 6 months; however this was not statistically significant.
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