ArticleNanomedicine (London, England)2015
Potentiation of antimicrobial photodynamic inactivation mediated by a cationic fullerene by added iodide: in vitro and in vivo studies.
Article in Nanomedicine (London, England), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
What it found
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Who cites it
46 citing papers in PubMed, 117 citations in OpenAlex.
- Nano-warfare in the oral cavity: antimicrobial strategies and mechanisms in nanodentistry.Odontology · 2026Review
- Enhanced 5-aminolevulinic acid photodynamic therapy with potassium iodide for sporotrichosis: in vitro optimization and a proof-of-concept clinical case.Tropical medicine and health · 2026Article
- Fullerene Gallium Phosphonate Shows Antimycobacterial Effect AgainstInternational journal of molecular sciences · 2025Article
- Selective Targeting and Enhanced Photodynamic Inactivation of Methicillin-ResistantAntibiotics (Basel, Switzerland) · 2025Article
- Photonics-based treatments: Mechanisms and applications in oral infectious diseases.Frontiers in microbiology · 2023Review
- Porphyrin Polymers BearingPolymers · 2022Article
- Development of a Polymeric Film Entrapping Rose Bengal and Iodide Anion for the Light-Induced Generation and Release of Bactericidal Hydrogen Peroxide.International journal of molecular sciences · 2022Article
- Application of Fullerenes as Photosensitizers for Antimicrobial Photodynamic Inactivation: A Review.Frontiers in microbiology · 2022Review
- Bioluminescent Models to Evaluate the Efficiency of Light-Based Antibacterial Approaches.Methods in molecular biology (Clifton, N.J.) · 2022Article
- Photodynamic control of citrus crop diseases.World journal of microbiology & biotechnology · 2021Review
- Porphyrin-Schiff Base Conjugates Bearing Basic Amino Groups as Antimicrobial Phototherapeutic Agents.Molecules (Basel, Switzerland) · 2021Article
- Antimicrobial Photodynamic Approach in the Inactivation of Viruses in Wastewater: Influence of Alternative Adjuvants.Antibiotics (Basel, Switzerland) · 2021Article
- A novel tricationic fullerene CPhotochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2021Article
- Article
- Antimicrobial Photodynamic Therapy in the Control ofMicroorganisms · 2020Article
- A powerful combination of copper-cysteamine nanoparticles with potassium iodide for bacterial destruction.Materials science & engineering. C, Materials for biological applications · 2020Article
- Considerations and Caveats in Combating ESKAPE Pathogens against Nosocomial Infections.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2020Review
- An Insight into Advanced Approaches for Photosensitizer Optimization in Endodontics-A Critical Review.Journal of functional biomaterials · 2019Article
- Tetracyclines: light-activated antibiotics?Future medicinal chemistry · 2019Review
- Can light-based approaches overcome antimicrobial resistance?Drug development research · 2019Review
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
Abstract
backgroundAntimicrobial photodynamic inactivation with fullerenes bearing cationic charges may overcome resistant microbes. METHODS &
resultsWe synthesized C60-fullerene (LC16) bearing decaquaternary chain and deca-tertiary-amino groups that facilitates electron-transfer reactions via the photoexcited fullerene. Addition of the harmless salt, potassium iodide (10 mM) potentiated the ultraviolet A (UVA) or white light-mediated killing of Gram-negative bacteria Acinetobacter baumannii, Gram-positive methicillin-resistant Staphylococcus aureus and fungal yeast Candida albicans by 1-2+ logs. Mouse model infected with bioluminescent Acinetobacter baumannii gave increased loss of bioluminescence when iodide (10 mM) was combined with LC16 and UVA/white light.
conclusionThe mechanism may involve photoinduced electron reduction of (1)(C60>)* or (3)(C60>)* by iodide producing I· or I2 followed by subsequent intermolecular electron-transfer events of (C60>)-· to produce reactive radicals.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.