Trial reportBioMed research international2015
Insufflation with humidified and heated carbon dioxide in short-term laparoscopy: a double-blinded randomized controlled trial.
Trial report in BioMed research international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 4 syntheses or guidelines pooled it, 28 citations in OpenAlex.
- Interventions to reduce shoulder pain following gynaecological laparoscopic procedures.The Cochrane database of systematic reviews · 2019Pooled it
- Warmed, humidified COAsian journal of endoscopic surgery · 2017Pooled it
- Warmed and humidified carbon dioxide for abdominal laparoscopic surgery: meta-analysis of the current literature.Surgical endoscopy · 2017Pooled it
- Heated insufflation with or without humidification for laparoscopic abdominal surgery.The Cochrane database of systematic reviews · 2016Pooled it
- The effect of warm and humidified gas insufflation in gynecological laparoscopy on maintenance of body temperature: a prospective randomized controlled multi-arm trial.Archives of gynecology and obstetrics · 2022Trial
- Warm and humidified insufflation gas during gynecologic laparoscopic surgery reduces postoperative pain in predisposed patients-a randomized, controlled multi-arm trial.Surgical endoscopy · 2022Trial
- Pain after laparoscopic surgery: Focus on shoulder-tip pain after gynecological laparoscopic surgery.Journal of the Chinese Medical Association : JCMA · 2019Review
- Prevention of Intraoperative Hypothermia in Laparoscopy by the Use of Body-Temperature and Humidified COGeburtshilfe und Frauenheilkunde · 2019Article
- Morpheus and the Underworld-Interventions to Reduce the Risks of Opioid Use After Surgery: ORADEs, Dependence, Cancer Progression, and Anastomotic Leakage.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2019Review
- Effects of Intraoperative Insufflation With Warmed, Humidified CO2 during Abdominal Surgery: A Review.Annals of coloproctology · 2018Article
- Changes in the coelomic microclimate during carbon dioxide laparoscopy: morphological and functional implications.Pleura and peritoneum · 2017Article
- Time Characteristics of Shoulder Pain after Laparoscopic Surgery.JSLS : Journal of the Society of Laparoendoscopic SurgeonsObservational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe tested the hypothesis that warm-humidified carbon dioxide (CO2) insufflation would reduce postoperative pain and morphine requirement compared to cold-dry CO2 insufflation.
methodsA double-blinded, randomized, controlled trial was conducted to compare warm, humidified CO2 and cold-dry CO2. Patients with benign uterine diseases were randomized to either treatment (n = 48) or control (n = 49) group during laparoscopically assisted vaginal hysterectomy. Primary endpoints of the study were rest pain, movement pain, shoulder-tip pain, and cough pain at 2, 4, 6, 24, and 48 hours postoperatively, measured by visual analogue scale. Secondary outcomes were morphine consumption, rejected boli, temperature change, recovery room stay, and length of hospital stay.
resultsThere were no significant differences in all baseline characteristics. Shoulder-tip pain at 6 h postoperatively was significantly reduced in the intervention group. Pain at rest, movement pain, and cough pain did not differ. Total morphine consumption and rejected boli at 24 h postoperatively were significantly higher in the control group. Temperature change, recovery room stay, and length of hospital were similar.
conclusionsWarm, humidified insufflation gas significantly reduces postoperative shoulder-tip pain as well as morphine demand. This trial is registered with Clinical Trial Registration Number DRKS00003853 (German Clinical Trials Register (DRKS)).
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.