Evidence map›Paper›PMID 25722859›Full record

ArticleOpen heart

Implementation of NICE Clinical Guideline 95 for assessment of stable chest pain in a rapid access chest pain clinic reduces the mean number of investigations and cost per patient.

Alvin J X Lee, Michael Michail, Shumonta A Quaderi, James A Richardson, Suneil K Aggarwal, M Elsya Speechly-Dick

Abstract read
In one paragraph

Article in Open heart. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Fast-track cardiology clinics-going Dutch!Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2019
    Article
  6. Review
  7. Article
  8. Myocardial perfusion imaging in women for the evaluation of stable ischemic heart disease-state-of-the-evidence and clinical recommendations.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017
    Article
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alvin J X LeeThe Heart Hospital, University College London Hospitals NHS Foundation Trust , London , UK ; University College London, Medical School , London , UK ; Medical Sciences Division , Academic Foundation Programme Doctor at the University of Oxford , Oxford , UK.
Michael MichailThe Heart Hospital, University College London Hospitals NHS Foundation Trust , London , UK.
Shumonta A QuaderiThe Heart Hospital, University College London Hospitals NHS Foundation Trust , London , UK.
James A RichardsonThe Heart Hospital, University College London Hospitals NHS Foundation Trust , London , UK.
Suneil K AggarwalThe Heart Hospital, University College London Hospitals NHS Foundation Trust , London , UK.
M Elsya Speechly-DickThe Heart Hospital, University College London Hospitals NHS Foundation Trust , London , UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveIn 2010, the National Institute for Health and Care Excellence (NICE) in the UK published Clinical Guideline 95 (CG95) advocating risk stratification of patients using 'CADScore' to guide appropriate cardiac investigations for chest pain of recent onset. Implementation of the guideline in the University College London Hospitals NHS Foundation Trust was evaluated to see if it led to a reduction in the average cost of the diagnostic journey per patient and fewer investigations per patient in order to confirm a diagnosis.

methodsThis was a single centre study at a Tertiary Centre in Central London. The investigative journey for each patient presenting to the Rapid Access Chest Pain Clinic (RACPC) at University College London Hospitals NHS Foundation Trust was recorded. Retrospective analysis on this data was performed.

resultsData for 4968 patients presenting to the RACPC from 2004 to 2012 was analysed and a size-matched cohort of 1503 patients preimplementation and postimplementation of the guidelines was compared. The mean cost of investigations postimplementation was £291.83 as compared to £319.54 preimplementation of the guidelines despite higher costs associated with some of the recommended initial investigations. The mean number of tests per patient postguidelines was 0.78 compared to 0.97 for preguidelines. An approximate twofold increase in patients not requiring tests was seen post-CG95 implementation (245 pre-CG95 vs 476 post-CG95).

conclusionsThe implementation of the NICE guidelines in our trust has reduced the average cost of the investigative journey and the number of investigations required per patient.

Indexed as

CORONARY ARTERY DISEASEIMAGING AND DIAGNOSTICS

Identifiers

PMID25722859
PMCPMC4336864

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.