Evidence map›Paper›PMID 25722713›Full record

ArticleNeural regeneration research2012

Paravertebral fascial massage promotes brain development of neonatal rats via the insulin-like growth factor 1 pathway.

Zhongqiu Wen, Wenqin Zeng, Jingxing Dai, Xin Zhou, Chun Yang, Fuhua Duan, Yufeng Liu, Huiying Yang, Lin Yuan

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neural regeneration research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Zhongqiu WenKey Laboratory of Tissue Construction and Detection of Guangdong Province, Department of Anatomy, Southern Medical University, Guangzhou 510515, Guangdong Province, China.
Wenqin ZengKey Laboratory of Tissue Construction and Detection of Guangdong Province, Department of Anatomy, Southern Medical University, Guangzhou 510515, Guangdong Province, China.
Jingxing DaiKey Laboratory of Tissue Construction and Detection of Guangdong Province, Department of Anatomy, Southern Medical University, Guangzhou 510515, Guangdong Province, China.
Xin ZhouKey Laboratory of Tissue Construction and Detection of Guangdong Province, Department of Anatomy, Southern Medical University, Guangzhou 510515, Guangdong Province, China.
Chun YangKey Laboratory of Tissue Construction and Detection of Guangdong Province, Department of Anatomy, Southern Medical University, Guangzhou 510515, Guangdong Province, China.
Fuhua DuanKey Laboratory of Tissue Construction and Detection of Guangdong Province, Department of Anatomy, Southern Medical University, Guangzhou 510515, Guangdong Province, China.
Yufeng LiuKey Laboratory of Tissue Construction and Detection of Guangdong Province, Department of Anatomy, Southern Medical University, Guangzhou 510515, Guangdong Province, China.
Huiying YangKey Laboratory of Tissue Construction and Detection of Guangdong Province, Department of Anatomy, Southern Medical University, Guangzhou 510515, Guangdong Province, China.
Lin YuanKey Laboratory of Tissue Construction and Detection of Guangdong Province, Department of Anatomy, Southern Medical University, Guangzhou 510515, Guangdong Province, China.
Southern Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Massage in traditional Chinese medicine can promote body and brain development of premature and normal newborn infants. In the present study, neonatal rats (1 day old) underwent paravertebral fascial massage (15 consecutive days), followed by subcutaneous injection of insulin-like growth factor 1 receptor antagonist, JB1 (9 consecutive days). Paravertebral fascial massage significantly increased insulin-like growth factor 1 expression and cell proliferation in the subventricular zone of the lateral ventricle and dentate gyrus of the hippocampus. However, JB1 inhibited this increase. Results suggest that paravertebral fascial massage can promote brain development of neonatal rats via the insulin-like growth factor 1 pathway.

Indexed as

immunohistochemistryinsulin-like growth factor 1neural regenerationneurogenesisparavertebral fascial massage

Identifiers

PMID25722713
PMCPMC4340037
OpenAlexW177675866

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.