Evidence map›Paper›PMID 25722649›Full record

ArticleThe Cochrane database of systematic reviews2014

A therapeutic-only versus prophylactic platelet transfusion strategy for preventing bleeding in patients with haematological disorders after chemotherapy or stem cell transplantation.

Lise J Estcourt, Gemma L Crighton, Erica M Wood, Simon Stanworth, Marialena Trivella, Carolyn Doree, Alan Tinmouth, Michael F Murphy

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Cochrane database of systematic reviews, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 syntheses or guidelines pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Lise J EstcourtHaematology/Transfusion Medicine, NHS Blood and Transplant, Oxford, UK.
Gemma L CrightonClinical Haematology, Royal Children' s Hospital Melbourne, Melbourne, Australia.
Erica M WoodDepartment of Clinical Haematology, Monash University, Melbourne, Australia.
Simon StanworthHaematology/Transfusion Medicine, NHS Blood and Transplant, Oxford, UK.
Marialena TrivellaCentre for Statistics in Medicine, University of Oxford, Oxford, UK.
Carolyn DoreeSystematic Review Initiative, NHS Blood and Transplant, Oxford, UK.
Alan TinmouthMedicine (hematology) and Pathology Centre for Transfusion Research, The Ottawa Health Research Institute and the University of Ottawa, Ottawa, Canada.
Michael F MurphyNHS Blood and Transplant, John Radcliffe Hospital, Oxford, UK.
NHS Blood and Transplant · GBJohn Radcliffe Hospital · GBMonash University · AUUniversity of Oxford · GB

Funding

Cancer Research UK 16895Department of Health 13/89/09Department of Health SRP/13/89/09
6 · The paper itself

Abstract

This is the protocol for a review and there is no abstract. The objectives are as follows: To determine whether a therapeutic-only platelet transfusion policy (platelet transfusions given when patient bleeds) is as effective and safe as a prophylactic platelet transfusion policy (platelet transfusions given to prevent bleeding usually when the platelet count falls below a given trigger level) in patients with haematological disorders undergoing myelosuppressive chemotherapy or stem cell transplantation.

Identifiers

PMID25722649
PMCPMC4338539
OpenAlexW1979071510

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.