Evidence map›Paper›PMID 25722437›Full record

ArticleCirculation research2015

Can the DNA damage response be harnessed to modulate atherosclerotic plaque phenotype?

Babak Razani, Elaine W Raines

Abstract readEditorialComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Circulation research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Babak RazaniFrom the Cardiovascular Division, Departments of Medicine and Pathology/Immunology, Washington University School of Medicine, St. Louis, MO (B.R.); and Department of Pathology, University of Washington School of Medicine, Seattle (E.W.R.). brazani@im.wustl.edu ewraines@uw.edu.
Elaine W RainesFrom the Cardiovascular Division, Departments of Medicine and Pathology/Immunology, Washington University School of Medicine, St. Louis, MO (B.R.); and Department of Pathology, University of Washington School of Medicine, Seattle (E.W.R.). brazani@im.wustl.edu ewraines@uw.edu.

Funding

Vector and Transgenic Mouse CoreP30DK017047 · NIDDK · UNIVERSITY OF WASHINGTON · PI Tomas Vaisar · 1986 to 2026
$41.4M
THE ROLE OF MACROPHAGE LYSOSOMAL BIOGENESIS IN ATHEROSCLEROSISR01HL125838 · NHLBI · WASHINGTON UNIVERSITY · PI RAZANI, BABAK · 2015 to 2025
$4.6M
Role of ADAMs in Endothelial Inflammatory ResponseR01HL067267 · NHLBI · UNIVERSITY OF WASHINGTON · PI BORNFELDT, KARIN E. · 2002 to 2015
$3.9M
De Novo Lipogenesis in Myocardial DysfunctionK08HL098559 · NHLBI · WASHINGTON UNIVERSITY · PI RAZANI, BABAK · 2010 to 2014
$589k
NHLBI NIH HHS HL067267NHLBI NIH HHS K08 HL098559NHLBI NIH HHS R01 HL067267NHLBI NIH HHS R01 HL125838NIDDK NIH HHS P30 DK017047
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

DNA DamageAnimalsFemaleHumansMaleMuscle, Smooth, VascularMyocytes, Smooth MusclePlaque, AtheroscleroticDNA breaks, double-strandedEditorialsmyocytes, smooth muscle

Identifiers

PMID25722437
PMCPMC4347866

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.