ArticleCell research2015
A novel chemopreventive strategy based on therapeutic microRNAs produced in plants.
Registry-linked trialAbstract readLetter
In one paragraph
Article in Cell research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04053569 (Effects of Polyphenols From a Table Grape on the Lipidomic Profile and Serum LDL Fractions), which is not on this map. Cited by 65 papers.
0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Polyphenols From a Table Grape on the Lipidomic Profile and Serum LDL Fractions: Possible Implications in the Metabolic Syndrome
Who cites it
65 citing papers in PubMed.
- An Apple a Day? The Hypothesis of Cross-Kingdom Gene Regulation by Plant miRNAs in Mammals and Its Controversies.International journal of molecular sciences · 2026Review
- Artificial MicroRNA delivery and gene silencing via extracellular vesicles derived from molecularly modified tobacco.Protoplasma · 2026Article
- Human miRNAs in Cancer: Statistical Trends and Cross Kingdom Approach.International journal of molecular sciences · 2025Article
- Exploring the bioactivity of MicroRNAs Originated from Plant-derived Exosome-like Nanoparticles (PELNs): current perspectives.Journal of nanobiotechnology · 2025Review
- Involvement of miRNAs in the Cluster of Metabolic Factors of MetS: Nutrition-Genome-MetS Axis.Journal of clinical medicine · 2025Review
- Plant miR6262 Modulates the Expression of Metabolic and Thermogenic Genes in Human Hepatocytes and Adipocytes.Nutrients · 2024Article
- Dietary Epigenetic Modulators: Unravelling the Still-Controversial Benefits of miRNAs in Nutrition and Disease.Nutrients · 2024Review
- Progress and challenges of plant-derived nucleic acids as therapeutics in macrophage-mediated RNA therapy.Frontiers in immunology · 2023Review
- Accurate quantification of 3'-terminal 2'-O-methylated small RNAs by utilizing oxidative deep sequencing and stem-loop RT-qPCR.Frontiers of medicine · 2022Article
- RNAi for Western Corn Rootworm Management: Lessons Learned, Challenges, and Future Directions.Insects · 2022Review
- Recent trends in miRNA therapeutics and the application of plant miRNA for prevention and treatment of human diseases.Future journal of pharmaceutical sciences · 2022Review
- The Challenges and Opportunities in the Development of MicroRNA Therapeutics: A Multidisciplinary Viewpoint.Cells · 2021Review
- Exosomes provide unappreciated carrier effects that assist transfers of their miRNAs to targeted cells; I. They are 'The Elephant in the Room'.RNA biology · 2021Review
- Plant-derived xenomiRs and cancer: Cross-kingdom gene regulation.Saudi journal of biological sciences · 2021Review
- miRNA in food simultaneously controls animal viral disease and human tumorigenesis.Molecular therapy. Nucleic acids · 2021Article
- SIDT1-dependent absorption in the stomach mediates host uptake of dietary and orally administered microRNAs.Cell research · 2021Article
- Perinatal and Early-Life Nutrition, Epigenetics, and Allergy.Nutrients · 2021Review
- Large-scale identification of extracellular plant miRNAs in mammals implicates their dietary intake.PloS one · 2021Article
- Potential Mechanisms Linking Food-Derived MicroRNAs, Gut Microbiota and Intestinal Barrier Functions in the Context of Nutrition and Human Health.Frontiers in nutrition · 2021Review
- A Timely Review of Cross-Kingdom Regulation of Plant-Derived MicroRNAs.Frontiers in genetics · 2021Review
5 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Sizolwenkosi MlotshwaDepartment of Biological Sciences, University of South Carolina, Columbia, SC 29208, USA;
Gail J PrussDepartment of Biological Sciences, University of South Carolina, Columbia, SC 29208, USA;
John L MacArthurDepartment of Biological Sciences, University of South Carolina, Columbia, SC 29208, USA;
Matthew W EndresDepartment of Biological Sciences, University of South Carolina, Columbia, SC 29208, USA;
Celestia DavisDepartment of Biological Sciences, University of South Carolina, Columbia, SC 29208, USA;
Lorne J HofsethDepartment of Drug Discovery and Biomedical Sciences, South Carolina College of Pharmacy, University of South Carolina, Columbia, SC 29208, USA.
Maria Marjorette PeñaDepartment of Biological Sciences, University of South Carolina, Columbia, SC 29208, USA;
Vicki VanceDepartment of Biological Sciences, University of South Carolina, Columbia, SC 29208, USA;
Funding
Targeting early ceramide elevation in pre-symptomatic eczemaP20GM103641 · NIGMS · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI ENOS, REILLY, NAGARKATTI, PRAKASH S · 2012 to 2023
$20.7MUse of Resveratrol to treat experimental multiple sclerosisP01AT003961 · NCCIH · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI NAGARKATTI, PRAKASH S · 2007 to 2018
$14.2MTISSUE BIOREPOSITORY COREP30GM103336 · NIGMS · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI BERGER, FRANKLIN G. · 2013 to 2017
$5.4MTargeting Protein Arginine Deiminases to Prevent Colitis and Colon CancerR01CA151304 · NCI · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI HOFSETH, LORNE J, THOMPSON, PAUL R · 2011 to 2015
$1.6MStromal modulation of response to Thymidylate synthase inhibitorsR01CA154731 · NCI · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI PENA, MARIA MARJORETTE · 2011 to 2015
$1.5MA Chemopreventive Strategy Based on Edible MicroRNAs Produced in PlantsR03CA181895 · NCI · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI VANCE, VICKI · 2014 to 2015
$147kNCCIH NIH HHS P01 AT003961NCI NIH HHS 1R03CA181895-01A1NCI NIH HHS 5R01CA151304NCI NIH HHS 5R01CA154731-04NCI NIH HHS R01 CA151304NCI NIH HHS R01 CA154731NCI NIH HHS R03 CA181895NIGMS NIH HHS 5P30 GM103336-02NIGMS NIH HHS P20 GM103641NIGMS NIH HHS P30 GM103336
Abstract
PubMed holds no abstract for this paper.
Indexed as
Gene Transfer TechniquesAdministration, OralAnimalsColonic NeoplasmsDisease Models, AnimalGenes, Tumor SuppressorGenetic TherapyMicroRNAsPlantsMicroRNAs
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
NCT04053569ClinicalTrials.gov
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.