ArticleEnvironmental research2015
The influence of obesity on blood mercury levels for U.S. non-pregnant adults and children: NHANES 2007-2010.
Article in Environmental research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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Who cites it
36 citing papers in PubMed.
- Endocrine-disrupting properties of heavy metal exposure contribute to the intergenerational effects on learning and memory.Frontiers in endocrinology · 2026Review
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- Associations of Metal Mixtures During Early Pregnancy With Midlife Obesity and Body Composition: A Prospective Study.Obesity (Silver Spring, Md.) · 2025Article
- Associations between environmental chemical mixtures and anthropometric measures in Korean girls: a cross-sectional study.European journal of pediatrics · 2025Article
- DNA methylation signatures of arsenic exposure and obesity.Environmental epigenetics · 2025Article
- Association of weight and dietary habits with high blood mercury levels in Korean adolescents: data from the KoNEHS cycle 4, 2018-2020.Annals of occupational and environmental medicine · 2025Article
- Investigation of the impact of exposure to trace elements on health and disease from the ToxiLaus study.Scientific reports · 2024Article
- Hair mercury isotopes, a noninvasive biomarker for dietary methylmercury exposure and biological uptake.Environmental science. Processes & impacts · 2024Article
- Proteomics, Human Environmental Exposure, and Cardiometabolic Risk.Circulation research · 2024Observational
- The association between heavy metal exposure and obesity: A systematic review and meta-analysis.Journal of diabetes and metabolic disorders · 2024Review
- Blood Concentration of Macro- and Microelements in Women Who Are Overweight/Obesity and Their Associations with Serum Biochemistry.Life (Basel, Switzerland) · 2024Article
- Environmental and genetic predictors of whole blood mercury and selenium concentrations in pregnant women in a UK birth cohort.Environmental advances · 2024Article
- Exposure to Metal Mixtures and Overweight or Obesity Among Chinese Adults.Biological trace element research · 2023Article
- Association of Blood Total Mercury with Dyslipidemia in a sample of U.S. Adolescents: Results from the National Health and Nutrition Examination Survey Database, 2011-2018.Hygiene and environmental health advances · 2023Article
- Characterization of the Plasmatic and Erythroid Multielemental Biodistribution in Childhood Obesity Using a High-Throughput Method for Size Fractionation of Metal Species.Methods in molecular biology (Clifton, N.J.) · 2023Article
- Relationship of blood heavy metals and osteoporosis among the middle-aged and elderly adults: A secondary analysis from NHANES 2013 to 2014 and 2017 to 2018.Frontiers in public health · 2023Article
- Relationship Between Serum Levels of Arsenic, Cadmium, and Mercury and Body Mass Index and Fasting Plasma Glucose in a Mexican Adult Population.Biological trace element research · 2022Article
- Article
- The Effect of Mixture of Heavy Metals on Obesity in Individuals ≥50 Years of Age.Biological trace element research · 2022Article
- Molecular Gatekeeper Discovery: Workflow for Linking Multiple Exposure Biomarkers to Metabolomics.Environmental science & technology · 2022Article
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3 authors.
Funding
Abstract
backgroundIn animal studies obesity is associated with higher blood and tissue mercury concentrations; however human studies are lacking. Although the mechanism underlying this association is uncertain, obesity may alter the metabolism and distribution of methylmercury.
objectivesWe determined whether obesity influenced blood mercury levels, the majority of which was methylmercury, for U.S. non-pregnant adults (≥20 years) and children (2-19 years) after controlling for methylmercury intake through fish and shellfish consumption, and other confounders.
methodsWe completed secondary data analysis of the National Health and Nutrition Examination Survey (NHANES) (2007-2010) for participants who consumed fish/shellfish within 24h of blood collection for mercury analysis. Weighted least squares regression models related blood mercury levels (the dependent variable) to methylmercury exposure (μg) from fish consumed in the previous 24h, body mass index (BMI) (for adults), BMI z-scores (for children), and other confounders.
resultsIn adjusted models, blood mercury levels were inversely correlated with BMI for adults [β, 95% confidence interval (CI)=-0.54 (-0.90, -0.18)]. For children, blood mercury levels were inversely correlated with BMI z-scores but the trend was not significant [β (95% CI)=-0.016 (-0.066, 0.035)]. When obese adults or children were compared with those who were overweight/normal weight, blood mercury averaged 22% lower for obese adults (95% CI: -33%, -8.2%), while blood mercury did not differ significantly for obese children [β (95% CI)=-1.7% (-31%, +39%)].
conclusionsAfter adjusting for the main, if not exclusive, exogenous source of methylmercury exposure (through fish/shellfish intake) and other confounders, our results support potential changes in the metabolism, distribution or excretion of methylmercury with increasing BMI (for adults).
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