Evidence map›Paper›PMID 25721184›Full record

Trial reportJournal of the American Academy of Child and Adolescent Psychiatry2015

Family-based interpersonal psychotherapy for depressed preadolescents: examining efficacy and potential treatment mechanisms.

Laura J Dietz, Rebecca J Weinberg, David A Brent, Laura Mufson

Registry-linked trialOpen access · greenAbstract readClinical Trial, Phase IIRandomized Controlled Trial
In one paragraph

Trial report in Journal of the American Academy of Child and Adolescent Psychiatry, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02054312 (Phase II Study of Family Based Interpersonal Psychotherapy), which is not on this map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
5.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02054312 nacompletednot on this map

Phase II Study of Family Based Interpersonal Psychotherapy (FB-IPT) for Depressed Preadolescents

TypeinterventionalSponsorUniversity of PittsburghRan2010 to 2014Enrolled42ConditionsDepressive DisordersArmsFamily Based Interpersonal Psychotherapy (FB-IPT), Client Centered Therapy (CCT)
3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 70 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
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  5. Trial
  6. Pilot Randomized Controlled Trial of Omega-3 and Individual-Family Psychoeducational Psychotherapy for Children and Adolescents With Depression.Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53 · 2019
    Trial
  7. The role of attachment style in interpersonal psychotherapy for depressed adolescents.Psychotherapy research : journal of the Society for Psychotherapy Research · 2019
    Trial
  8. Trial
  9. Trial
  10. Article
  11. Article
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  14. Review
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  18. "Third-wave" cognitive and behavioral therapies and the emergence of a process-based approach to intervention in psychiatry.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2021
    Article
  19. Psychological Treatments for Depression in Adolescents: More Than Three Decades Later.International journal of environmental research and public health · 2021
    Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Laura J DietzUniversity of Pittsburgh School of Medicine, Pittsburgh. Electronic address: dietzlj@upmc.edu.
Rebecca J WeinbergUniversity of Pittsburgh School of Medicine, Pittsburgh.
David A BrentUniversity of Pittsburgh School of Medicine, Pittsburgh.
Laura MufsonColumbia University College of Physicians and Surgeons/New York State Psychiatric Institute (NYSPI), New York.
University of Pittsburgh · USNew York State Psychiatric Institute

Funding

Family Based Interpersonal Psychotherapy (IPT) for Depressed PreadolescentsK23MH079353 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DIETZ, LAURA J · 2008 to 2012
$715k
NIMH NIH HHS K23 MH079353NIMH NIH HHS MH 079353
6 · The paper itself

Abstract

objectiveTo conduct a randomized controlled trial to evaluate the preliminary efficacy of family-based interpersonal psychotherapy (FB-IPT) for treating depression in preadolescents (aged 7-12 years) as compared to child-centered therapy (CCT), a supportive and nondirective treatment that closely approximates the standard of care for pediatric depression in community mental health.

methodPreadolescents with depression (N = 42) were randomly assigned FB-IPT or CCT. Pre- and posttreatment assessments included clinician-administered measures of depression, parent- and child-reported depression and anxiety symptoms, and parent-child conflict and interpersonal impairment with peers.

resultsPreadolescents receiving FB-IPT had higher rates of remission (66.0% versus 31%), a greater decrease in depressive symptoms from pre- to posttreatment, and lower depressive symptoms at posttreatment (R(2) = 0.35, ΔR(2) = 0.22; B = -8.15, SE = 2.61, t[37] = -3.13, p = .002, F(2) = 0.28) than did preadolescents with depression receiving CCT. Furthermore, preadolescents in the FB-IPT condition reported significant reductions in anxiety and interpersonal impairment compared with preadolescents in the CCT condition. Changes in social and peer impairment from pre- to posttreatment were associated with preadolescents' posttreatment depressive symptoms. There was a significant indirect effect for decreased social impairment accounting for the association between the FB-IPT and preadolescents' posttreatment depressive symptoms.

conclusionFindings indicate FB-IPT is an effective treatment for preadolescent depression and support further investigation of interpersonal mechanisms by which FB-IPT may reduce preadolescent depression. Clinical trial registration information-Phase II Study of Family Based Interpersonal Psychotherapy (FB-IPT) for Depressed Preadolescents; http://clinicaltrials.gov; NCT02054312.

Indexed as

Interpersonal RelationsAnxietyChildDepressionDepressive DisorderFamily TherapyFemaleHumansLinear ModelsMalePennsylvaniaPerson-Centered PsychotherapyPsychiatric Status Rating ScalesTreatment OutcomedepressionIPTpreadolescentrandomized controlled trialtreatment

Identifiers

PMID25721184
PMCPMC4347931
OpenAlexW2083078293

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.