Evidence map›Paper›PMID 25721077›Full record

ArticleAJNR. American journal of neuroradiology2015

Changes of time-attenuation curve blood flow parameters in patients with and without carotid stenosis.

C-J Lin, F-C Chang, W-Y Guo, S-C Hung, C-B Luo, J Beilner, M Kowarschik, W-F Chu

Abstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Experimental study using phantom models of cerebral aneurysms and 4D-DSA to measure blood flow on 3D-color-coded images.Technology and health care : official journal of the European Society for Engineering and Medicine · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

C-J LinFrom the Department of Radiology (C.-J.L., F.-C.C., W.-Y.G., S.-C.H., C.-B.L., W.-F.C.), Taipei Veterans General Hospital, Taipei, Taiwan School of Medicine (C.-J.L., F.-C.C., W.-Y.G., S.-C.H., C.-B.L.), National Yang-Ming University, Taipei, Taiwan.
F-C ChangFrom the Department of Radiology (C.-J.L., F.-C.C., W.-Y.G., S.-C.H., C.-B.L., W.-F.C.), Taipei Veterans General Hospital, Taipei, Taiwan School of Medicine (C.-J.L., F.-C.C., W.-Y.G., S.-C.H., C.-B.L.), National Yang-Ming University, Taipei, Taiwan.
W-Y GuoFrom the Department of Radiology (C.-J.L., F.-C.C., W.-Y.G., S.-C.H., C.-B.L., W.-F.C.), Taipei Veterans General Hospital, Taipei, Taiwan School of Medicine (C.-J.L., F.-C.C., W.-Y.G., S.-C.H., C.-B.L.), National Yang-Ming University, Taipei, Taiwan wyguo@vghtpe.gov.tw.
S-C HungFrom the Department of Radiology (C.-J.L., F.-C.C., W.-Y.G., S.-C.H., C.-B.L., W.-F.C.), Taipei Veterans General Hospital, Taipei, Taiwan School of Medicine (C.-J.L., F.-C.C., W.-Y.G., S.-C.H., C.-B.L.), National Yang-Ming University, Taipei, Taiwan.
C-B LuoFrom the Department of Radiology (C.-J.L., F.-C.C., W.-Y.G., S.-C.H., C.-B.L., W.-F.C.), Taipei Veterans General Hospital, Taipei, Taiwan School of Medicine (C.-J.L., F.-C.C., W.-Y.G., S.-C.H., C.-B.L.), National Yang-Ming University, Taipei, Taiwan.
J BeilnerAngiography and Interventional X-Ray Systems (J.B.), Siemens Ltd China, Healthcare Sector, Shanghai, P.R. China.
M KowarschikAngiography and Interventional X-Ray Systems (M.K.), Siemens AG, Healthcare Sector, Erlangen, Germany.
W-F ChuFrom the Department of Radiology (C.-J.L., F.-C.C., W.-Y.G., S.-C.H., C.-B.L., W.-F.C.), Taipei Veterans General Hospital, Taipei, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeFrom the time-attenuation curves of DSA flow parameters, maximal intensity, maximal slope, and full width at half maximum of selected vascular points are defined. The study explores the reliability of defining the flow parameters by the time-attenuation curves of DSA. MATERIALS AND

methodsSeventy patients with unilateral carotid artery stenosis (group A) and 56 healthy controls (group B) were retrospectively enrolled. Fixed contrast injection protocols and DSA acquisition parameters were used with all patients. The M1, sigmoid sinus, and internal jugular vein on anteroposterior view DSA and the M2, parietal vein, and superior sagittal sinus on lateral view DSA were chosen as ROI targets for measuring flow parameters. The difference of time of maximal intensity between 2 target points was defined as the circulation time between the target points.

resultsThe maximal intensity difference of 2 selected points from the ICA to the M1, sigmoid sinus, internal jugular vein, M2, parietal vein, and superior sagittal sinus was significantly longer in group A than in group B. The maximum slope of M1, M2, and the superior sagittal sinus was significantly lower in group A than in group B. The full width at half maximum of M1 and M2 was significantly larger in group A than in group B. The maximal slope of M1 demonstrated the best diagnostic performance.

conclusionsThe maximal intensity difference of 2 selected points derived from DSA can be used as a definitive alternative flow parameter for intracranial circulation time measurement. Maximal slope and full width at half maximum complement the maximal intensity difference of 2 selected points in defining flow characteristics of healthy subjects and patients with carotid stenosis.

Indexed as

AdultAgedAngiography, Digital SubtractionBlood Flow VelocityCarotid StenosisCase-Control StudiesContrast MediaFemaleHumansImage Interpretation, Computer-AssistedMaleMiddle AgedRadiographic Image EnhancementReproducibility of ResultsRetrospective StudiesSensitivity and SpecificityContrast Media

Identifiers

PMID25721077
PMCPMC8013018

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.