ArticleNature2015
Antibodies: The solution is validation.
Article in Nature, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Guidelines for authors and reviewers on antibody use in physiology studies.American journal of physiology. Heart and circulatory physiology · 2018Guideline
- High-Efficiency Genomic Mapping of Chromatin-Associated Targets with CUT&RUN.Methods in molecular biology (Clifton, N.J.) · 2026Article
- Antibody characterization is critical to enhance reproducibility in biomedical research.eLife · 2024Review
- Antibody validation for protein expression on tissue slides: a protocol for immunohistochemistry.BioTechniques · 2020Article
- Fast Confirmation of Antibody Identity by MALDI-TOF MS Fingerprints.Antibodies (Basel, Switzerland) · 2020Article
- The supply chain of human pancreatic β cell lines.The Journal of clinical investigation · 2019Review
- Ten Basic Rules of Antibody Validation.Analytical chemistry insights · 2018Review
- Enhancing the toolbox to study IL-17A in cattle and sheep.Veterinary research · 2017Article
- Generation of Murine Monoclonal Antibodies by Hybridoma Technology.Journal of visualized experiments : JoVE · 2017Article
- Quality Issues of Research Antibodies.Analytical chemistry insights · 2016Review
- Antibodies: validate recombinants once.Nature · 2015Article
- A ChIP on the shoulder? Chromatin immunoprecipitation and validation strategies for ChIP antibodies.F1000Research · 2015Review
- Article
- Animal- versusmAbsArticle
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
25719656What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.