Evidence map›Paper›PMID 25719614›Full record

ReviewPain2015

Inhibitory regulation of the pain gate and how its failure causes pathological pain.

Theodore J Price, Steven A Prescott

Abstract readReview
In one paragraph

Review in Pain, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Pharmacological and Genetic Approaches to Downregulate FIS1 Mitigate Neuropathic Pain.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  5. Article
  6. Neuropathic pain; what we know and what we should do about it.Frontiers in pain research (Lausanne, Switzerland) · 2023
    Review
  7. Excitatory and Inhibitory Neurons of the Spinal Cord Superficial Dorsal Horn Diverge in Their Somatosensory Responses and PlasticityThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2022
    Article
  8. A Female-Specific Role for Calcitonin Gene-Related Peptide (CGRP) in Rodent Pain Models.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022
    Article
  9. Article
  10. Spinal Inhibitory Interneurons: Gatekeepers of Sensorimotor Pathways.International journal of molecular sciences · 2021
    Review
  11. Review
  12. Reversal of peripheral nerve injury-induced neuropathic pain and cognitive dysfunction via genetic and tomivosertib targeting of MNK.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2020
    Article
  13. Article
  14. Review
  15. The MNK-eIF4E Signaling Axis Contributes to Injury-Induced Nociceptive Plasticity and the Development of Chronic Pain.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017
    Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Theodore J PriceSchool of Behavioral and Brain Sciences, University of Texas at Dallas, Richardson, TX, USA The Hospital for Sick Children, Program in Neurosciences and Mental Health, Department of Physiology, University of Toronto, Toronto, ON, Canada.
Steven A Prescott

Funding

Translation Control of Pain PlasticityR01NS065926 · NINDS · UNIVERSITY OF TEXAS DALLAS · PI PRICE, THEODORE J. · 2010 to 2023
$5.7M
AMPK ACTIVATORS FOR THE TREATMENT OF POST-SURGICAL PAINR01GM102575 · NIGMS · UNIVERSITY OF TEXAS DALLAS · PI DUSSOR, GREGORY O, PRICE, THEODORE J. · 2013 to 2016
$1.1M
Canadian Institutes of Health ResearchNIGMS NIH HHS R01 GM102575NIGMS NIH HHS R01GM102575NINDS NIH HHS R01 NS065926NINDS NIH HHS R01NS065926
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Neural InhibitionAnimalsgamma-Aminobutyric AcidHumansNeurotransmitter AgentsPainPain MeasurementPosterior Horn CellsSignal Transductiongamma-Aminobutyric AcidNeurotransmitter Agents

Identifiers

PMID25719614
PMCPMC4589225

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.