ArticleSaudi medical journal2015
Frequency and associated risk factors of recurrent diabetic ketoacidosis among Saudi adolescents with type 1 diabetes mellitus.
Article in Saudi medical journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 69 citations in OpenAlex.
- A Systematic Review of Childhood Diabetes Research in the Middle East Region.Frontiers in endocrinology · 2019Pooled it
- Determinants of Quality of Life in Saudi Adults with Type 2 Diabetes Mellitus: A Cross-Sectional Study in Jeddah.Healthcare (Basel, Switzerland) · 2026Article
- Clinical profile of diabetic ketoacidosis and its severity in adults: evidence from ALERT Comprehensive Specialized Hospital.BMC endocrine disorders · 2026Article
- Precipitating factors and clinical outcomes of diabetic ketoacidosis in Eastern Cape, South Africa.Journal of the colleges of medicine of South Africa · 2025Article
- Article
- Clinical variables influencing the severity of diabetes ketoacidosis.Saudi medical journal · 2024Article
- Patterns and Characteristics of Diabetic Ketoacidosis in Children With Type I Diabetes in Saudi Arabia.Cureus · 2024Article
- Diabetic Ketoacidosis After COVID-19 Vaccine in Patients with Type 1 Diabetes Mellitus.International journal of endocrinology and metabolism · 2023Article
- An Audit of Factors Impacting the Time to Resolution of the Metabolic Parameters in Diabetic Ketoacidosis Patients.Cureus · 2022Article
- Non-Occlusive Mesenteric Ischemia in Children With Diabetic Ketoacidosis: Case Report and Review of Literature.Frontiers in endocrinology · 2022Review
- Frequency and Risk Factors of Diabetic Ketoacidosis in a Specialized Children's Hospital, Riyadh: A Cross-sectional Study.Oman medical journal · 2022Article
- Article
- Management of Diabetic Ketoacidosis in Children and Adolescents with Type 1 Diabetes Mellitus.Paediatric drugs · 2020Review
- Pediatric diabetes in Saudi Arabia: Challenges and potential solutions. A review article.International journal of pediatrics & adolescent medicine · 2019Review
- Insulin-Related Lipohypertrophy: Lipogenic Action or Tissue Trauma?Frontiers in endocrinology · 2018Article
- Type 1 Diabetes Mellitus in Saudi Arabia: A Soaring Epidemic.International journal of pediatrics · 2018Review
- Double diabetes in Saudi Arabia: A new entity or an underestimated condition.World journal of diabetes · 2016Article
- Frequency of Lipohypertrophy and Associated Risk Factors in Young Patients with Type 1 Diabetes: A Cross-Sectional Study.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2016Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo explore the frequency and associated risk factors of recurrent diabetic ketoacidosis (RDKA) among Saudi adolescents with type 1 diabetes mellitus (T1DM).
methodsA cross-sectional study was conducted among 103 T1DM adolescents (aged 13-18 years, 57 males) who were hospitalized for diabetic ketoacidosis (DKA) between January 2013 and May 2014 at Prince Sultan Military Medical City (PSMMC), Riyadh, Kingdom of Saudi Arabia. The respondents were purposively, conveniently selected, and interviewed using a structured Arabic questionnaire including clinical information and demographics.
resultsFifty-six participants had experienced one episode of DKA, 41 had 2 episodes, and 6 had ≥3 episodes. Compared with adolescents who had hemoglobin A1c (HbA1c) ≤9, mean difference in RDKA was found among adolescents with >9 HbA1c. Similarly, adolescents who stopped insulin and those with lipodystrophy at the injection site had a higher frequency of RDKA. Discontinuing insulin (67%) was the major reason for RDKA followed by infection (31%). Among adolescents who discontinued insulin treatment, 31 (46.3%) gave no reason for stopping, 25 (37.3%) reported feeling sick, 7 (10.4%) gave a combination of reasons, and 4 (6%) reported a lack of supplies or other reasons. Regression analysis revealed that a higher HbA1c level and the presence of lipodystrophy were independent risk factors for RDKA.
conclusionThe frequency of RDKA was significantly greater in the T1DM adolescents with a higher HbA1c level, lipodystrophy, and those who had discontinued insulin treatment. Comprehensive multidisciplinary diabetes education should be offered to control modifiable risk factors in these patients.
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