Evidence map›Paper›PMID 25719546›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2015

Does chronic oxygen dependency in preterm infants with bronchopulmonary dysplasia at NICU discharge predict respiratory outcomes at 3 years of age?

A Lodha, K Ediger, Y Rabi, S Lodha, S Tang, A Bhandari, R Sauve, V Bhandari

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. In-hospital outcomes of premature infants with severe bronchopulmonary dysplasia.Journal of perinatology : official journal of the California Perinatal Association · 2017
    Article
  4. Inter-center variation in death or tracheostomy placement in infants with severe bronchopulmonary dysplasia.Journal of perinatology : official journal of the California Perinatal Association · 2017
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

A Lodha1] Department of Pediatrics, University of Calgary, Calgary, Alberta, Canada [2] Department of Pediatrics, Alberta Children's Hospital Research Institute, Calgary, Alberta, Canada [3] Department of Pediatrics, Alberta Health Services, Calgary, Alberta, Canada [4] Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.
K EdigerDepartment of Pediatrics, University of Calgary, Calgary, Alberta, Canada.
Y Rabi1] Department of Pediatrics, University of Calgary, Calgary, Alberta, Canada [2] Department of Pediatrics, Alberta Children's Hospital Research Institute, Calgary, Alberta, Canada [3] Department of Pediatrics, Alberta Health Services, Calgary, Alberta, Canada.
S LodhaDepartment of Pediatrics, University of Calgary, Calgary, Alberta, Canada.
S TangDepartment of Pediatrics, Alberta Health Services, Calgary, Alberta, Canada.
A BhandariDepartment of Pediatric Pulmonology, Connecticut Children's Medical Center, Hartford, CT, USA.
R Sauve1] Department of Pediatrics, University of Calgary, Calgary, Alberta, Canada [2] Department of Pediatrics, Alberta Children's Hospital Research Institute, Calgary, Alberta, Canada [3] Department of Pediatrics, Alberta Health Services, Calgary, Alberta, Canada.
V BhandariDepartment of Pediatrics, Yale University, New Haven, CT, USA.
University of Calgary · CAAlberta Health Services · CAConnecticut Children's Medical Center · USYale University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine whether chronic oxygen dependency at the time of discharge from the neonatal intensive care unit (NICU) in infants with bronchopulmonary dysplasia (BPD) predicts respiratory outcomes at 3 years. STUDY

designPreterm infants ⩽1250 g without BPD, BPD and BPD with chronic oxygen dependency were identified from the Southern Alberta Perinatal Follow-up clinic database (1995-2007). Respiratory outcomes at 4, 8, 18 and 36 months corrected age following NICU discharge were examined. Univariate analyses were done.

resultsOut of 1563 infants admitted to the NICU, 1212 survived. Complete follow-up data at 36 months were available for 1030 (85%) children. Children with BPD with or without chronic oxygen dependency had significantly (P<0.001) lower birth weights and gestational ages, and greater post-natal steroid use, compared with those with no BPD. At 4, 8 and 18 months follow-up, the use of respiratory medications and supplemental oxygen were both significantly higher in the BPD infants with chronic oxygen dependency group compared with the no-BPD group and BPD group. At 36 months, children in the BPD with chronic oxygen dependency group were more likely to use respiratory medications and supplemental oxygen vs the no-BPD or the BPD groups. At 4, 8 and 36 months of age, more children in the BPD with chronic oxygen dependency group had post-neonatal chronic lung disease (PNCLD) than children in the other groups, but at 36 months the difference was significant only for the BPD with chronic oxygen dependency vs no-BPD group (P<0.001).

conclusionsAt 36 months, children diagnosed with BPD with chronic oxygen dependency at NICU discharge were more likely to need respiratory medications and supplemental oxygen in the previous 12 months, as compared with no-BPD or BPD groups. They were also more likely to require frequent physician visits and have PNCLD at 3 years, as compared with the no-BPD group.

Indexed as

Oxygen Inhalation TherapyPatient DischargeBirth WeightBronchopulmonary DysplasiaChild, PreschoolChronic DiseaseFemaleGestational AgeHumansInfantInfant, NewbornInfant, PrematureIntensive Care Units, NeonatalLongitudinal StudiesMaleOutcome Assessment, Health Care

Identifiers

PMID25719546
OpenAlexW2092766056

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.